[HTML][HTML] Current non-metal nanoparticle-based therapeutic approaches for glioblastoma treatment

AM Gawel, A Betkowska, E Gajda, M Godlewska… - Biomedicines, 2024 - mdpi.com
The increase in the variety of nano-based tools offers new possibilities to approach the
therapy of poorly treatable tumors, which includes glioblastoma multiforme (GBM; a primary …

Mechanism of Action and Design of Potent Antibacterial Block Copolymer Nanoparticles

HC Parkin, STG Street, B Gowen… - Journal of the …, 2024 - ACS Publications
Self-assembled polymer nanoparticles are promising antibacterials, with nonspherical
morphologies of particular interest as recent work has demonstrated enhanced antibacterial …

Functional Noncentrosymmetric Nanoparticle–Nanofiber Hybrids via Selective Fragmentation

HK MacKenzie, Y Zhang, W Zheng… - Journal of the …, 2024 - ACS Publications
Noncentrosymmetric nanostructures are an attractive synthetic target as they can exhibit
complex interparticle interactions useful for numerous applications. However, generating …

Uniform polyester-based nanoparticles assembled via living crystallization-driven self-assembly as friction-reducing agents in engine oil

C Clamor, SD Dale, J Beament, E Mould… - …, 2023 - ACS Publications
Develo** new friction modifiers with enhanced green credentials for the automotive
industry is imperative to reduce man-made global warming. Recently, polymer-based …

Mesogenic Ordering–Driven Self–Assembly of Liquid Crystalline Block Copolymers in Solution

B **, L Hu, X Li - Chemistry–A European Journal, 2024 - Wiley Online Library
With the development of nanotechnology, the preparation of polymeric nanoparticles with
nicely defined structures has been well–developed, and the functionalization and …

Optimization of precision nanofiber micelleplexes for DNA delivery

STG Street, HC Parkin, L Shopperly, J Chrenek… - Biomaterials …, 2023 - pubs.rsc.org
As nucleic acid (NA) technologies continue to revolutionize medicine, new delivery vehicles
are needed to effectively transport NA cargoes into cells. Uniform and length-tunable …

Manipulation of Macrophage Uptake by Controlling the Aspect Ratio of Graft Copolymer Micelles

Y Sakamoto, S Fujii, S Takano, J Fukushima… - Nano Letters, 2024 - ACS Publications
Nanostructures of drug carriers play a crucial role in nanomedicine due to their ability to
influence drug delivery. There is yet no clear consensus regarding the optimal size and …

Length-Dependent Cellular Internalization of Nanobody-Functionalized Poly (2-oxazoline) Nanorods

JR Finnegan, LI FitzGerald, MZ Chen, NM Warne… - Nano Letters, 2023 - ACS Publications
The ability to target specific tissues and to be internalized by cells is critical for successful
nanoparticle-based targeted drug delivery. Here, we combined “stealthy” rod-shaped poly (2 …

Uniform block copolymer nanofibers for the delivery of paclitaxel in 2D and 3D glioblastoma tumor models

HC Parkin, LK Shopperly, MR Perez, SM Willerth… - Biomaterials …, 2024 - pubs.rsc.org
Cancer treatment has transformed in recent years, with the introduction of immunotherapy
providing substantial improvements in prognoses for certain cancers. However, traditional …

Ian Manners (1961-2023): Learning to Fly.

E Leitao, H MacKenzie - Angewandte Chemie (International ed. in …, 2024 - europepmc.org
Ian Manners, an internationally renowned main-group and materials scientist, passed away
on December 3, 2023. He will be remembered as a brilliant researcher, an avid …