Thyroid hormone transporters at the plasma membrane govern intracellular bioavailability of
thyroid hormone. Monocarboxylate transporter (MCT) 8 and MCT10, organic anion …

The cellular influx and efflux of thyroid hormones are facilitated by transmembrane protein
transporters. Of these transporters, monocarboxylate transporter 8 (MCT8) is the only one …

Inactivating mutations in the thyroid hormone (TH) transporter Monocarboxylate transporter
8 (MCT8) cause severe psychomotor retardation in children. Animal models do not reflect …

Abstract The Zebrafish Model Organism Database (ZFIN; https://zfin. org) is the central
resource for genetic, genomic, and phenotypic data for zebrafish (Danio rerio) research …

Thyroid hormone system disrupting compounds are considered potential threats for human
and environmental health. Multiple adverse outcome pathways (AOPs) for thyroid hormone …

The effects and underlying mechanisms of phthalates on neurotoxicity remain unclear as
compared with the potentials of these substances as endocrine disruptors. The locomotor …

Triclosan (TCS) is an organic compound with a wide range of antibiotic activity and has
been widely used in items ranging from hygiene products to cosmetics; however, recent …

Fragile X syndrome (FXS) is the most frequent inherited form of mental retardation. The
cause for this X-linked disorder is the silencing of the fragile X mental retardation 1 (fmr1) …

Sleep is widely recognized as essential, but without a clear singular function. Inadequate
sleep impairs cognition, metabolism, immune function, and many other processes. Work in …

Background: Mutations in the thyroid hormone (TH) transporter monocarboxylate transporter
8 (MCT8) lead to peripheral hyperthyroidism and profound psychomotor alterations in …