Histotripsy is a relatively new therapeutic ultrasound technology to mechanically liquefy
tissue into subcellular debris using high-amplitude focused ultrasound pulses. In contrast to …

Cancer is a devasting disease resulting in millions of deaths worldwide in both humans and
companion animals, including dogs. Treatment of cancer is complex and challenging and …

Background: Osteosarcoma (OS) is the most frequently occurring malignant bone tumor in
humans, primarily affecting children and adolescents. Significant advancements in treatment …

Simple Summary Histotripsy is a non-invasive focused ultrasound therapy, in development,
for treating osteosarcoma (OS). Small pilot studies describing ex vivo and in vivo histotripsy …

Histotripsy is the first noninvasive, non-ionizing, and non-thermal ablation technique that
mechanically fractionates target tissue into acellular homogenate via controlled acoustic …

Background Osteosarcoma (OS) is the most frequently occurring primary bone tumor in dogs
and people and innovative treatment options are profoundly needed. Histotripsy is an …

Purpose Feline soft tissue sarcoma (STS) and injection site sarcoma (fISS) are rapidly
growing tumors with low metastatic potential, but locally aggressive behavior. Histotripsy is a …

Mechanical high-intensity focused ultrasound (M-HIFU), which includes histotripsy, is a non-
ionizing, non-thermal ablation technology that can be delivered by noninvasive methods …

Histotripsy is an ultrasound-guided, noninvasive, nonthermal ablation therapy that can
mechanically lyse target tissues. There have been no reports of enhanced histotripsy for …

Introduction: For venous thrombosis patients, catheter-directed thrombolytic therapy is the
standard-of-care to recanalize the occluded vessel. Limitations with thrombolytic drugs make …