Beginning with the introduction of Fourier Transform NMR by Ernst and Anderson in 1966,
time domain measurement of the impulse response (the free induction decay, FID) consisted …

Modern high-field NMR instruments provide unprecedented resolution. To make use of the
resolving power in multidimensional NMR experiment standard linear sampling through the …

The fast Fourier transformation has been the gold standard for transforming data from time to
frequency domain in many spectroscopic methods, including NMR. While reliable, it has as …

Non-uniform sampling is shown to provide significant time savings in the acquisition of a
suite of three-dimensional NMR experiments utilized for obtaining backbone assignments of …

Since its discovery in mid-20th century, the sensitivity of Nuclear Magnetic Resonance
(NMR) has increased steadily, in part due to the design of new, sophisticated NMR …

Multi-dimensional NMR spectra have traditionally been processed with the fast Fourier
transformation (FFT). The availability of high field instruments, the complexity of spectra of …

We introduce the recursive multidimensional decomposition (R-MDD) method to speed
recording of high-resolution NMR spectra. The measurement time is logarithmically …

Highlights•Large monomeric proteins suffer from spectral crowding.•Nonuniform sampling of
3D and 4D data optimizes spectral resolution.•Selective methyl labeling and tailored NMR …

NMR spectroscopy is one of the most powerful and versatile analytic tools available to
chemists. The discrete Fourier transform (DFT) played a seminal role in the development of …

It is well established that non-uniform sampling (NUS) allows acquisition of multi-
dimensional NMR spectra at a resolution that cannot be obtained with traditional uniform …