Freezing revisited: coordinated autonomic and central optimization of threat co**
Animals have sophisticated mechanisms for co** with danger. Freezing is a unique state
that, upon threat detection, allows evidence to be gathered, response possibilities to be …
that, upon threat detection, allows evidence to be gathered, response possibilities to be …
The role of the hippocampus in the consolidation of emotional memories during sleep
Episodic memory relies on the hippocampus, a heterogeneous brain region with distinct
functions. Spatial representations in the dorsal hippocampus (dHPC) are crucial for …
functions. Spatial representations in the dorsal hippocampus (dHPC) are crucial for …
Breathing coordinates cortico-hippocampal dynamics in mice during offline states
Network dynamics have been proposed as a mechanistic substrate for the information
transfer across cortical and hippocampal circuits. However, little is known about the …
transfer across cortical and hippocampal circuits. However, little is known about the …
Preservation of a remote fear memory requires new myelin formation
Experience-dependent myelination is hypothesized to shape neural circuit function and
subsequent behavioral output. Using a contextual fear memory task in mice, we demonstrate …
subsequent behavioral output. Using a contextual fear memory task in mice, we demonstrate …
Temporal evolution of cortical ensembles promoting remote memory retrieval
Memories of fearful events can last a lifetime. The prelimbic (PL) cortex, a subregion of
prefrontal cortex, plays a critical role in fear memory retrieval over time. Most studies have …
prefrontal cortex, plays a critical role in fear memory retrieval over time. Most studies have …
Respiration-entrained brain rhythms are global but often overlooked
We revisit recent evidence showing that nasal respiration entrains oscillations at the same
frequency as breathing in several regions of the rodent brain. Moreover, respiration …
frequency as breathing in several regions of the rodent brain. Moreover, respiration …
[HTML][HTML] Synaptic plasticity, engrams, and network oscillations in amygdala circuits for storage and retrieval of emotional memories
The neuronal circuits of the basolateral amygdala (BLA) are crucial for acquisition,
consolidation, retrieval, and extinction of associative emotional memories. Synaptic plasticity …
consolidation, retrieval, and extinction of associative emotional memories. Synaptic plasticity …
Amygdala inputs to prefrontal cortex guide behavior amid conflicting cues of reward and punishment
Orchestrating appropriate behavioral responses in the face of competing signals that predict
either rewards or threats in the environment is crucial for survival. The basolateral nucleus of …
either rewards or threats in the environment is crucial for survival. The basolateral nucleus of …
Breathing-driven prefrontal oscillations regulate maintenance of conditioned-fear evoked freezing independently of initiation
Brain–body interactions are thought to be essential in emotions but their physiological basis
remains poorly understood. In mice, regular 4 Hz breathing appears during freezing after …
remains poorly understood. In mice, regular 4 Hz breathing appears during freezing after …
Impact of anxiety on prefrontal cortex encoding of cognitive flexibility
Anxiety often is studied as a stand-alone construct in laboratory models. But in the context of
co** with real-life anxiety, its negative impacts extend beyond aversive feelings and …
co** with real-life anxiety, its negative impacts extend beyond aversive feelings and …