Transition metal-catalyzed tandem reactions of ynamides for divergent N-heterocycle synthesis

FL Hong, LW Ye - Accounts of Chemical Research, 2020 - ACS Publications
Conspectus Ynamides are electron-rich heteroatom-substituted alkynes with a C–C triple
bond directly attached to the amide group. Importantly, this amide group is able to impose an …

Transition metal-catalyzed C–H amination: scope, mechanism, and applications

Y Park, Y Kim, S Chang - Chemical reviews, 2017 - ACS Publications
Catalytic transformation of ubiquitous C–H bonds into valuable C–N bonds offers an efficient
synthetic approach to construct N-functionalized molecules. Over the last few decades …

Gold-catalyzed synthesis of small rings

M Mato, A Franchino, C Garcı́a-Morales… - Chemical …, 2020 - ACS Publications
Three-and four-membered rings, widespread motifs in nature and medicinal chemistry, have
fascinated chemists ever since their discovery. However, due to energetic considerations …

Copper-catalyzed C–H functionalization reactions: efficient synthesis of heterocycles

XX Guo, DW Gu, Z Wu, W Zhang - Chemical reviews, 2015 - ACS Publications
Copper-Catalyzed C–H Functionalization Reactions: Efficient Synthesis of Heterocycles |
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Aerobic copper-catalyzed organic reactions

SE Allen, RR Walvoord, R Padilla-Salinas… - Chemical …, 2013 - ACS Publications
The chemistry of copper is extremely rich because it can easily access Cu0, CuI, CuII, and
CuIII oxidation states allowing it to act through one-electron or two-electron processes. As a …

Copper-catalyzed aerobic oxidations of organic molecules: pathways for two-electron oxidation with a four-electron oxidant and a one-electron redox-active catalyst

SD McCann, SS Stahl - Accounts of Chemical Research, 2015 - ACS Publications
Conspectus Selective oxidation reactions have extraordinary value in organic chemistry,
ranging from the conversion of petrochemical feedstocks into industrial chemicals and …

Bond formations between two nucleophiles: transition metal catalyzed oxidative cross-coupling reactions

C Liu, H Zhang, W Shi, A Lei - Chemical Reviews, 2011 - ACS Publications
In chemistry, a nucleophile is a molecule or ion with a lone pair of electrons. It donates both
bonding electrons to its reaction partner (the electrophile) when forming a chemical bond. 1 …

Copper‐Catalyzed Aerobic Oxidative C H Functionalizations: Trends and Mechanistic Insights

AE Wendlandt, AM Suess… - Angewandte Chemie …, 2011 - Wiley Online Library
The selective oxidation of C H bonds and the use of O2 as a stoichiometric oxidant
represent two prominent challenges in organic chemistry. Copper (II) is a versatile oxidant …

High-valent organometallic copper and palladium in catalysis

AJ Hickman, MS Sanford - Nature, 2012 - nature.com
Copper and palladium catalysts are critically important in numerous commercial chemical
processes. Improvements in the activity, selectivity and scope of these catalysts could …

Overcoming the “Oxidant Problem”: Strategies to Use O2 as the Oxidant in Organometallic C–H Oxidation Reactions Catalyzed by Pd (and Cu)

AN Campbell, SS Stahl - Accounts of chemical research, 2012 - ACS Publications
Oxidation reactions are key transformations in organic chemistry because they can increase
chemical complexity and incorporate heteroatom substituents into carbon-based molecules …