Aging hallmarks and the role of oxidative stress
E Maldonado, S Morales-Pison, F Urbina, A Solari - Antioxidants, 2023 - mdpi.com
Aging is a complex biological process accompanied by a progressive decline in the physical
function of the organism and an increased risk of age-related chronic diseases such as …
function of the organism and an increased risk of age-related chronic diseases such as …
The senescence-associated secretory phenotype (SASP) in the challenging future of cancer therapy and age-related diseases
L Cuollo, F Antonangeli, A Santoni, A Soriani - Biology, 2020 - mdpi.com
Simple Summary A fundamental feature of cellular senescence is the emergence of the
Senescence-Associated Secretory Phenotype (SASP), which represents a considerable …
Senescence-Associated Secretory Phenotype (SASP), which represents a considerable …
The how and why of lncRNA function: an innate immune perspective
Next-generation sequencing has provided a more complete picture of the composition of the
human transcriptome indicating that much of the “blueprint” is a vastness of poorly …
human transcriptome indicating that much of the “blueprint” is a vastness of poorly …
MicroRNAome genome: a treasure for cancer diagnosis and therapy
I Berindan‐Neagoe, PC Monroig… - CA: a cancer journal …, 2014 - Wiley Online Library
The interplay between abnormalities in genes coding for proteins and noncoding
microRNAs (miRNAs) has been among the most exciting yet unexpected discoveries in …
microRNAs (miRNAs) has been among the most exciting yet unexpected discoveries in …
Non-coding RNAs: the new central dogma of cancer biology
The central dogma of molecular biology states that the functions of RNA revolve around
protein translation. Until the last decade, most researches were geared towards …
protein translation. Until the last decade, most researches were geared towards …
Long non-coding RNAs in the regulation of the immune response
It is increasingly clear that long non-coding RNAs (lncRNAs) regulate a variety biological
responses, and that they do so by a diverse range of mechanisms. In the field of …
responses, and that they do so by a diverse range of mechanisms. In the field of …
Noncoding RNAs, cytokines, and inflammation‐related diseases
JL Marques‐Rocha, M Samblas, FI Milagro… - The FASEB …, 2015 - Wiley Online Library
Chronic inflammation is involved in the onset and development of many diseases, including
obesity, atherosclerosis, type 2 diabetes, osteoarthritis, autoimmune and degenerative …
obesity, atherosclerosis, type 2 diabetes, osteoarthritis, autoimmune and degenerative …
[HTML][HTML] Long non-coding RNAs: Mechanism of action and functional utility
Recent RNA sequencing studies have revealed that most of the human genome is
transcribed, but very little of the total transcriptomes has the ability to encode proteins. Long …
transcribed, but very little of the total transcriptomes has the ability to encode proteins. Long …
Non-coding RNAs and exosomes: their role in the pathogenesis of sepsis
Sepsis is characterized as an uncontrolled host response to infection, and it represents a
serious health challenge, causing excess mortality and morbidity worldwide. The discovery …
serious health challenge, causing excess mortality and morbidity worldwide. The discovery …
Long noncoding RNA (lincRNA), a new paradigm in gene expression control
Long intergenic non-coding RNAs (lincRNAs) are defined as RNA transcripts that are longer
than 200 nucleotides. By definition, these RNAs must not have open reading frames that …
than 200 nucleotides. By definition, these RNAs must not have open reading frames that …