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Recent insights into the etiopathogenesis of diabetic retinopathy and its management
A Biswas, AD Choudhury, S Agrawal… - Journal of Ocular …, 2024 - liebertpub.com
Purpose: Diabetic retinopathy (DR) is a microvascular retinal disease associated with
chronic diabetes mellitus, characterized by the damage of blood vessels in the eye. It is …
chronic diabetes mellitus, characterized by the damage of blood vessels in the eye. It is …
Diabetic retinopathy: new treatment approaches targeting redox and immune mechanisms
Q Tang, F Buonfiglio, EW Böhm, L Zhang, N Pfeiffer… - Antioxidants, 2024 - mdpi.com
Diabetic retinopathy (DR) represents a severe complication of diabetes mellitus,
characterized by irreversible visual impairment resulting from microvascular abnormalities …
characterized by irreversible visual impairment resulting from microvascular abnormalities …
Oxidative stress, inflammatory, angiogenic, and apoptotic molecules in proliferative diabetic retinopathy and diabetic macular edema patients
I Andrés-Blasco, A Gallego-Martínez… - International journal of …, 2023 - mdpi.com
The aim of this study is to evaluate molecules involved in oxidative stress (OS),
inflammation, angiogenesis, and apoptosis, and discern which of these are more likely to be …
inflammation, angiogenesis, and apoptosis, and discern which of these are more likely to be …
Optical coherence tomography in the management of diabetic macular oedema
Diabetic macular oedema (DMO) is the major cause of visual impairment in people with
diabetes. Optical coherence tomography (OCT) is now the most widely used modality to …
diabetes. Optical coherence tomography (OCT) is now the most widely used modality to …
TIN2 modulates FOXO1 mitochondrial shuttling to enhance oxidative stress-induced apoptosis in retinal pigment epithelium under hyperglycemia
S Chen, D Sun, S Zhang, L Xu, N Wang, H Li… - Cell Death & …, 2024 - nature.com
Progressive dysfunction of the retinal pigment epithelium (RPE) and the adjacent
photoreceptor cells in the outer retina plays a pivotal role in the pathogenesis of diabetic …
photoreceptor cells in the outer retina plays a pivotal role in the pathogenesis of diabetic …
Next generation therapeutics for retinal neurodegenerative diseases
MB Appell, J Pejavar, A Pasupathy… - Journal of Controlled …, 2024 - Elsevier
Neurodegenerative diseases affecting the visual system encompass glaucoma, macular
degeneration, retinopathies, and inherited genetic disorders such as retinitis pigmentosa …
degeneration, retinopathies, and inherited genetic disorders such as retinitis pigmentosa …
Chondrocyte‐Targeted Delivery System of Sortase A‐Engineered Extracellular Vesicles Silencing MMP13 for Osteoarthritis Therapy
W Yan, Y Li, S **e, WA Tao, J Hu, H Liu… - Advanced …, 2024 - Wiley Online Library
Targeted drug delivery and the reduction of off‐target effects are crucial for the promising
clinical application of nucleic acid drugs. To address this challenge, a new approach for …
clinical application of nucleic acid drugs. To address this challenge, a new approach for …
Effects and potential mechanisms of exercise and physical activity on eye health and ocular diseases
Q Zhang, Y Jiang, C Deng, J Wang - Frontiers in Medicine, 2024 - frontiersin.org
In the field of eye health, the profound impact of exercise and physical activity on various
ocular diseases has become a focal point of attention. This review summarizes and …
ocular diseases has become a focal point of attention. This review summarizes and …
Interleukin-17A in diabetic retinopathy: the crosstalk of inflammation and angiogenesis
J Li, T Zhao, Y Sun - Biochemical Pharmacology, 2024 - Elsevier
Diabetic retinopathy (DR) is a severe ocular complication of diabetes which can leads to
irreversible vision loss in its late-stage. Chronic inflammation results from long-term …
irreversible vision loss in its late-stage. Chronic inflammation results from long-term …
[HTML][HTML] Advancements in Ocular Therapy: A Review of Emerging Drug Delivery Approaches and Pharmaceutical Technologies
Eye disorders affect a substantial portion of the global population, yet the availability of
efficacious ophthalmic drug products remains limited. This can be partly ascribed to a …
efficacious ophthalmic drug products remains limited. This can be partly ascribed to a …