Immunology of acute and chronic wound healing

K Raziyeva, Y Kim, Z Zharkinbekov, K Kassymbek… - Biomolecules, 2021 - mdpi.com
Skin wounds greatly affect the global healthcare system, creating a substantial burden on
the economy and society. Moreover, the situation is exacerbated by low healing rates, which …

Biomaterials functionalized with MSC secreted extracellular vesicles and soluble factors for tissue regeneration

MÁ Brennan, P Layrolle… - Advanced functional …, 2020 - Wiley Online Library
The therapeutic benefits of mesenchymal stromal cell (MSC) transplantation are attributed to
their secreted factors, including extracellular vesicles (EVs) and soluble factors. The …

Hyaluronic acid in ocular drug delivery

X Zhang, D Wei, Y Xu, Q Zhu - Carbohydrate Polymers, 2021 - Elsevier
As a naturally-occurring polysaccharide which could be found in various ophthalmic tissues,
hyaluronic acid (HA) has a wide range of applications in the eye, including treatment of dry …

Nanozyme‐incorporated microneedles for the treatment of chronic wounds

Z Hu, J Shan, Y Cui, L Cheng… - Advanced Healthcare …, 2024 - Wiley Online Library
Acute wounds are converted to chronic wounds due to advanced age and diabetic
complications. Nanozymes catalyze ROS production to kill bacteria without causing drug …

[HTML][HTML] Corneal regeneration strategies: From stem cell therapy to tissue engineered stem cell scaffolds

M Wang, Y Li, H Wang, M Li, X Wang, R Liu… - Biomedicine & …, 2023 - Elsevier
Corneal epithelial defects and excessive wound healing might lead to severe complications.
As stem cells can self-renew infinitely, they are a promising solution for regenerating the …

[HTML][HTML] Advances in extracellular vesicle functionalization strategies for tissue regeneration

D Zheng, H Ruan, W Chen, Y Zhang, W Cui, H Chen… - Bioactive Materials, 2023 - Elsevier
Extracellular vesicles (EVs) are nano-scale vesicles derived by cell secretion with unique
advantages such as promoting cell proliferation, anti-inflammation, promoting blood vessels …

Glycosaminoglycans in tissue engineering: a review

H Sodhi, A Panitch - Biomolecules, 2020 - mdpi.com
Glycosaminoglycans are native components of the extracellular matrix that drive cell
behavior and control the microenvironment surrounding cells, making them promising …

Characterizing the impact of 2D and 3D culture conditions on the therapeutic effects of human mesenchymal stem cell secretome on corneal wound healing in vitro …

K Carter, HJ Lee, KS Na, GM Fernandes-Cunha… - Acta biomaterialia, 2019 - Elsevier
The therapeutic effects of secreted factors (secretome) produced by bone marrow-derived
human mesenchymal stem cells (MSCs) were evaluated as a function of their growth in 2D …

[HTML][HTML] MiRNA 24-3p-rich exosomes functionalized DEGMA-modified hyaluronic acid hydrogels for corneal epithelial healing

X Sun, W Song, L Teng, Y Huang, J Liu, Y Peng, X Lu… - Bioactive Materials, 2023 - Elsevier
The damage of corneal epithelium may lead to the formation of irreversible corneal opacities
and even blindness. The migration rate of corneal epithelial cells directly affects corneal …

Chondroitin sulfate-based composites: a tour d'horizon of their biomedical applications

MAS Abourehab, S Baisakhiya, A Aggarwal… - Journal of Materials …, 2022 - pubs.rsc.org
Chondroitin sulfate (CS), a natural anionic mucopolysaccharide, belonging to the
glycosaminoglycan family, acts as the primary element of the extracellular matrix (ECM) of …