Nanoparticles as drug delivery system have received much attention in recent years,
especially for cancer treatment. In addition to improving the pharmacokinetics of the loaded …

Since the elucidation of the molecular structure of nucleic acids and understanding of their
role in encoding and translating genetic information into biological function, 1 the knowledge …

Dendrimers are novel three dimensional, hyperbranched globular nanopolymeric
architectures. Attractive features like nanoscopic size, narrow polydispersity index, excellent …

Polyethylenimine (PEI) has recently been widely studied for the design of nucleic acid
delivery vehicles. Gene delivery using PEI involves condensation of DNA into compact …

Stimuli-responsive polymers show a sharp change in properties upon a small or modest
change in environmental condition, eg temperature, light, salt concentration or pH. This …

Gene therapy has gained significant attention over the past two decades as a potential
method for treating genetic disorders such as severe combined immunodeficiency, 1 cystic …

The formation of particulate systems with well-defined sizes and shapes is of eminent
interest in certain medical applications such as drug delivery, gene transfection, and …

The Michael addition reaction is a versatile synthetic methodology for the efficient coupling
of electron poor olefins with a vast array of nucleophiles. This review outlines the role of the …

Therapeutics based on RNA interference mechanisms are highly promising for the
management of several diseases including multi-drug resistant cancers. However, effective …

Magnetic nanoparticles have been proved as a tremendously powerful synthetic tool to
achieve a milder process for the organic transformations and also suggested many …