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[HTML][HTML] Emerging SARS-CoV-2 variants of concern (VOCs): an impending global crisis
The worldwide battle against the SARS-CoV-2 virus rages on, with millions infected and
many innocent lives lost. The causative organism, severe acute respiratory syndrome …
many innocent lives lost. The causative organism, severe acute respiratory syndrome …
Role of senescence and aging in SARS-CoV-2 infection and COVID-19 disease
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has resulted in a global pandemic associated with substantial …
coronavirus 2 (SARS-CoV-2), has resulted in a global pandemic associated with substantial …
Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity
Abstract The SARS-CoV-2 Omicron BA. 1 variant emerged in 2021 and has multiple
mutations in its spike protein. Here we show that the spike protein of Omicron has a higher …
mutations in its spike protein. Here we show that the spike protein of Omicron has a higher …
SARS-CoV-2 B. 1.617. 2 Delta variant replication and immune evasion
Abstract The B. 1.617. 2 (Delta) variant of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) was first identified in the state of Maharashtra in late 2020 and spread …
(SARS-CoV-2) was first identified in the state of Maharashtra in late 2020 and spread …
[HTML][HTML] Antibody resistance of SARS-CoV-2 variants B. 1.351 and B. 1.1. 7
The COVID-19 pandemic has had widespread effects across the globe, and its causative
agent, SARS-CoV-2, continues to spread. Effective interventions need to be developed to …
agent, SARS-CoV-2, continues to spread. Effective interventions need to be developed to …
[HTML][HTML] Experimental evidence for enhanced receptor binding by rapidly spreading SARS-CoV-2 variants
Rapidly spreading new variants of SARS-CoV-2 carry multiple mutations in the viral spike
protein which attaches to the angiotensin converting enzyme 2 (ACE2) receptor on host …
protein which attaches to the angiotensin converting enzyme 2 (ACE2) receptor on host …
Recurrent emergence and transmission of a SARS-CoV-2 spike deletion H69/V70
SARS-CoV-2 amino acid replacements in the receptor binding domain (RBD) occur
relatively frequently and some have a consequence for immune recognition. Here we report …
relatively frequently and some have a consequence for immune recognition. Here we report …
[HTML][HTML] The emergence and ongoing convergent evolution of the SARS-CoV-2 N501Y lineages
The independent emergence late in 2020 of the B. 1.1. 7, B. 1.351, and P. 1 lineages of
SARS-CoV-2 prompted renewed concerns about the evolutionary capacity of this virus to …
SARS-CoV-2 prompted renewed concerns about the evolutionary capacity of this virus to …
[HTML][HTML] Risk of hospitalisation associated with infection with SARS-CoV-2 lineage B. 1.1. 7 in Denmark: an observational cohort study
Background The more infectious SARS-CoV-2 lineage B. 1.1. 7 rapidly spread in Europe
after December, 2020, and a concern that B. 1.1. 7 could cause more severe disease has …
after December, 2020, and a concern that B. 1.1. 7 could cause more severe disease has …
SARS-CoV-2 Omicron spike mediated immune escape and tropism shift
Abstract The SARS-CoV-2 Omicron BA. 1 variant emerged in late 2021 and is characterised
by multiple spike mutations across all spike domains. Here we show that Omicron BA. 1 has …
by multiple spike mutations across all spike domains. Here we show that Omicron BA. 1 has …