Dissipative formation of covalent basket cages

VW Liyana Gunawardana, TJ Finnegan… - Angewandte …, 2022 - Wiley Online Library
Living systems use chemical fuels to transiently assemble functional structures. As a step
toward constructing abiotic mimics of such structures, we herein describe dissipative …

From selection to instruction and back: competing conformational selection and induced fit pathways in abiotic hosts

RZ Pavlović, RF Lalisse, AL Hansen… - Angewandte Chemie …, 2021 - Wiley Online Library
Two limiting cases of molecular recognition, induced fit (IF) and conformational selection
(CS), play a central role in allosteric regulation of natural systems. The IF paradigm states …

On the Selectivity in the Synthesis of 3-Fluoropiperidines Using BF3-Activated Hypervalent Iodine Reagents

RZ Pavlović, TJ Kop, M Nesic… - The Journal of …, 2023 - ACS Publications
Fluorinated piperidines find wide applications, most notably in the development of novel
therapies and agrochemicals. Cyclization of alkenyl N-tosylamides promoted by BF3 …

Control and transfer of chirality within well-defined tripodal supramolecular cages

G Qiu, P Nava, C Colomban, A Martinez - Frontiers in Chemistry, 2020 - frontiersin.org
The development of new strategies to turn achiral artificial hosts into highly desirable chiral
receptors is a crucial challenge in order to advance the fields of asymmetric transformations …

Supersensitive detection of anions in pure organic and aqueous media by amino acid conjugated Ellman's reagent

S Dhawan, H Devnani, J Babu, H Singh… - ACS Applied Bio …, 2021 - ACS Publications
The last few decades witnessed a remarkable advancement in the field of molecular anion
receptors. A variety of anion binding motifs have been discovered, and large number of …

Photoinduced interruption of interannular cooperativity for delivery of cationic guests in water

RZ Pavlović, SE Border, Y Li, X Li… - Chemical …, 2020 - pubs.rsc.org
The synergy among twelve carboxylates from two hexavalent baskets 16− assisted the
encapsulation of one divalent diammonium guest 32+–62+ and the formation of ternary [3 …

A computational study of competing conformational selection and induced fit in an abiotic system

RF Lalisse, RZ Pavlović, CM Hadad… - Physical Chemistry …, 2022 - pubs.rsc.org
Host–guest complexations can be described by two competing mechanisms, conformational
selection (CS) and induced fit (IF). In this work, we used a combination of nudged elastic …

Rationalization of chirality transfer and fast conformational changes in a tris (2-pyridylmethyl) amine-based cage

G Qiu, DE Khatmi, A Martinez, P Nava - RSC advances, 2021 - pubs.rsc.org
The key features that govern the chirality transfer in a structurally contracted covalent cage,
consisting of a northern chiral cyclotriveratrylene (CTV) connected to a southern tris (2 …

Bridged benzocyclotrimers: concepts, synthesis, and applications

S Cossu, P Peluso - Current Organic Chemistry, 2021 - ingentaconnect.com
Bridged polycyclic frameworks represent a unique tool to form curved units; the bicyclo [2.2.
1] hepta-2, 5-diene system is widely exploited to design and induce concave topologies. In …

A Molecular Capsule with Revolving Doors Partitioning Its Inner Space

Z Lei, TJ Finnegan, VWL Gunawardana… - … A European Journal, 2020 - Wiley Online Library
Covalent capsule 1 was designed to include two molecular baskets linked with three mobile
pyridines tucked into its inner space. On the basis of both theory (DFT) and experiments …