Evidence from clinical, preclinical, and post-mortem studies supports the
inflammatory/immune hypothesis of schizophrenia pathogenesis. Less evident is the link …

Microglia are the tissue-resident immune cells of the central nervous system, where they
constitute the first line of defense against any pathogens or injury. Microglia are highly motile …

The actin motor protein non-muscle myosin II (NMII) acts as a master regulator of cell
morphology, with a role in several essential cellular processes, including cell migration and …

Myosins are among the most fascinating enzymes in biology. As extremely allosteric
chemomechanical molecular machines, myosins are involved in myriad pivotal cellular …

Microglia, commonly known as the tissue resident macrophages of the central nervous
system (CNS), are ubiquitously expressed in the CNS. Microglia, in their resting, or …

Myosins are a remarkable superfamily of actin-based motor proteins that use the energy
derived from ATP hydrolysis to translocate actin filaments and to produce force. Myosins are …

Myosins are motor proteins that use chemical energy to produce mechanical forces driving
actin cytoskeletal dynamics. In the brain, the conventional non-muscle myosin II (NMII) …

The brain cells are affected by continuous fluid shear stress that is driven by varying
hydrostatic and osmotic pressure conditions, depending on the brain's pathophysiological …

Microglia are the most prominent immune resident cell population in the central nervous
system (CNS). In the healthy CNS, microglia survey their surrounding microenvironment …

Microglia are present throughout the central nervous system (CNS) and express receptors
for every known neurotransmitter. During inflammation, microglia change into a state that …