Nutrigenetics and nutrigenomics hold much promise for providing better nutritional advice to
the public generally, genetic subgroups and individuals. Because nutrigenetics and …

Simple Summary In this review, the authors propose a crosswise examination of cytarabine-
related issues ranging from the spectrum of clinical activity and severe toxicities, through …

The MMR system has evolved to increase the fidelity of DNA replication and homologous
recombination1. MMR is also implicated in the processing of other types of DNA damage, as …

There has been much progress in genomics in the ten years since a draft sequence of the
human genome was published. Opportunities for understanding health and disease are now …

Identifying targets of positive selection in humans has, until recently, been frustratingly slow,
relying on the analysis of individual candidate genes. Genomics, however, has provided the …

This is the tenth update of the human obesity gene map, incorporating published results up
to the end of October 2003 and continuing the previous format. Evidence from single‐gene …

Pharmacogenetics provides opportunities for informed decision-making along the
pharmaceutical pipeline. There is a growing literature of retrospective studies of marketed …

Abstract The Bermuda Principles for DNA sequence data sharing are an enduring legacy of
the Human Genome Project (HGP). They were adopted by the HGP at a strategy meeting in …

We report a whole-genome shotgun assembly (called WGSA) of the human genome
generated at Celera in 2001. The Celera-generated shotgun data set consisted of 27 million …

The analysis of single nucleotide polymorphisms (SNPs) is increasingly utilizedto
investigate the genetic causes of complex human diseases. Here we present a high …