Transfusion-associated circulatory overload (TACO) and transfusion-related acute lung
injury (TRALI) are syndromes of acute respiratory distress that occur within 6 hours of blood …

Platelets are most often recognized for their crucial role in the control of acute hemorrhage.
However, current research has greatly expanded the appreciation of platelets beyond their …

The prevention and management of bleeding and thrombosis in patients with cirrhosis
poses several difficult clinical questions. These Clinical Practice Guidelines have been …

Platelets are anucleate cells that are crucial mediators of haemostasis. Most immunologists
probably don't think about platelets every day, and may even consider these cells to …

Transfusion-related acute lung injury (TRALI) and transfusion-associated circulatory
overload (TACO) are the leading causes of transfusion-related morbidity and mortality …

Background: Transfusion-related acute lung injury (TRALI) is now the leading cause of
transfusion-associated mortality, even though it is probably still underdiagnosed and …

Since the adult respiratory distress syndrome was first described substantial progress has
been made in understanding the pathogenesis of this complex syndrome. This review …

Transfusion-related acute lung injury (TRALI) is the leading cause of transfusion-associated
mortality in the US. Previously, we established an immune-mediated TRALI mouse model …

Although platelets are best known as primary mediators of hemostasis, this function
intimately associates them with inflammatory processes, and it has been increasingly …

Rationale: Acute lung injury (ALI) that develops 6 hours after transfusion (TRALI) is the
leading cause of transfusion-related mortality. Several transfusion characteristics have been …