One of the most powerful strategies to investigate biology we have as scientists, is the ability
to transfer genetic material in a controlled and deliberate manner between organisms. When …

Mesenchymal stem cells have awakened a great deal of interest in regenerative medicine
due to their plasticity, and immunomodulatory and anti-inflammatory properties. They are …

This review deals with the latest advances in the study of embryonic stem cells (ESC) and
induced pluripotent stem cells (iPSC) from domesticated species, with a focus on pigs, cattle …

Circular RNAs (circRNAs) have been found to be a crucial role in stem cell-associated bone
regeneration. However, the functions and underlying mechanisms of circRNAs in the …

Induced pluripotent stem cells (iPSCs) are a seminal breakthrough in stem cell research and
are promising tools for advanced regenerative therapies in humans and reproductive …

Until recently, it has been difficult to derive and maintain stable embryonic stem cells lines
from livestock species. Sheep ESCs with characteristics similar to those described for …

Pluripotent stem cells are unspecialized cells with unlimited self-renewal, and they can be
triggered to differentiate into desired specialized cell types. These features provide the basis …

The unlimited proliferative ability and capacity to contribute to germline chimeras make
pluripotent embryonic stem cells (ESCs) perfect candidates for complex genetic …

Pluripotent stem cells such as embryonic stem cells (ESCs) and induced pluripotent stem
cells (iPSCs) provide great potential as cell sources for gene editing to generate genetically …

Background Low back pain is a leading cause of disability worldwide and is frequently
attributed to intervertebral disc (IVD) degeneration. Though the contributions of the adjacent …