Association between immune-related side effects and efficacy and benefit of immune checkpoint inhibitors–a systematic review and meta-analysis
S Hussaini, R Chehade, RG Boldt, J Raphael… - Cancer Treatment …, 2021 - Elsevier
Background The use of immune checkpoint inhibitors (ICIs) has become standard therapy in
many tumor sites. The aim of this study is to systematically review the literature to determine …
many tumor sites. The aim of this study is to systematically review the literature to determine …
Harnessing big data to characterize immune-related adverse events
Immune-checkpoint inhibitors (ICIs) have transformed patient care in oncology but are
associated with a unique spectrum of organ-specific inflammatory toxicities known as …
associated with a unique spectrum of organ-specific inflammatory toxicities known as …
Immune checkpoint inhibitor-associated colitis: from mechanism to management
L Tang, J Wang, N Lin, Y Zhou, W He, J Liu… - Frontiers in …, 2021 - frontiersin.org
Immune checkpoint inhibitors (ICIs), as one of the innovative types of immunotherapies,
including programmed cell death-1 (PD-1), programmed cell death-ligand 1 (PD-L1), and …
including programmed cell death-1 (PD-1), programmed cell death-ligand 1 (PD-L1), and …
Resumption of immune checkpoint inhibitor therapy after immune-mediated colitis
PURPOSE Immune checkpoint inhibitor (ICI) therapy often is suspended because of
immune-mediated diarrhea and colitis (IMDC). We examined the rate of and risk factors for …
immune-mediated diarrhea and colitis (IMDC). We examined the rate of and risk factors for …
[HTML][HTML] Rechallenge patients with immune checkpoint inhibitors following severe immune-related adverse events: review of the literature and suggested prophylactic …
J Haanen, M Ernstoff, Y Wang, A Menzies… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Patients with cancer who developed severe, grade 3 or 4 immune-related adverse events
(irAEs) during therapy with immune checkpoint inhibitors are at risk for develo** severe …
(irAEs) during therapy with immune checkpoint inhibitors are at risk for develo** severe …
Association of immune related adverse events with efficacy of immune checkpoint inhibitors and overall survival in cancers: a systemic review and meta-analysis
Y Fan, W **e, H Huang, Y Wang, G Li, Y Geng… - Frontiers in …, 2021 - frontiersin.org
Objectives Immune checkpoint inhibitors (ICIs) have brought impressive benefits to cancer
patients, however often accompanied with immune-related adverse events (irAEs). We …
patients, however often accompanied with immune-related adverse events (irAEs). We …
Checkpoint inhibitor–induced colitis
E Bellaguarda, S Hanauer - … journal of the American College of …, 2020 - journals.lww.com
Immune checkpoint inhibitors have revolutionized treatment and overall survival for several
different types of cancer. Antibodies to cytotoxic T-lymphocyte-associated protein 4 and to …
different types of cancer. Antibodies to cytotoxic T-lymphocyte-associated protein 4 and to …
Gut microbiome for predicting immune checkpoint blockade-associated adverse events
M Hu, X Lin, T Sun, X Shao, X Huang, W Du, M Guo… - Genome Medicine, 2024 - Springer
Background The impact of the gut microbiome on the initiation and intensity of immune-
related adverse events (irAEs) prompted by immune checkpoint inhibitors (ICIs) is widely …
related adverse events (irAEs) prompted by immune checkpoint inhibitors (ICIs) is widely …
Immune-related adverse events: promising predictors for efficacy of immune checkpoint inhibitors
L Zhong, Q Wu, F Chen, J Liu, X **e - Cancer Immunology …, 2021 - Springer
Purpose This study was designed to investigate the correlation between immune-related
adverse events (irAEs) of immune checkpoint inhibitors (ICIs) and corresponding efficacy …
adverse events (irAEs) of immune checkpoint inhibitors (ICIs) and corresponding efficacy …
Immune-related adverse events (irAE) in cancer immune checkpoint inhibitors (ICI) and survival outcomes correlation: to rechallenge or not?
HJ Albandar, J Fuqua, JM Albandar, S Safi, SA Merrill… - Cancers, 2021 - mdpi.com
Simple Summary This study examined the real-world experience and occurrence of immune-
related adverse events (irAEs) under cancer checkpoint immunotherapy, and the …
related adverse events (irAEs) under cancer checkpoint immunotherapy, and the …