Metformin (MF), a first-line drug to treat type 2 diabetes mellitus (T2DM), alone and in
combination with other drugs, restores the ovarian function in women with polycystic ovary …

Objective The objective of this clinical practice guideline is to provide updated and new
evidence-based recommendations for the comprehensive care of persons with diabetes …

An overview of the sperm metabolism is presented; using the stallion as a model we review
glycolysis, Krebs Cycle and oxidative phosphorylation, paying special attention to the …

The global rise in obesity and steady decline in sperm quality are two alarming trends that
have emerged during recent decades. In parallel, evidence from model organisms shows …

Background The present study performed two distinct meta-analyses with common
outcomes (sperm parameters); one was performed in obese individuals (and non-obese …

STUDY QUESTION How knowledgeable are men about the medical, environmental and
psychological factors that are associated with male infertility? SUMMARY ANSWER Men …

Background Some evidence suggests that diabetes mellitus type 1 (DM1) could affect male
fertility, gonadal axis, semen parameters, and spermatogenesis because of effects of …

Diabetes mellitus (DM) is a multifaceted and costly disease, which requires serious
attention. Finding a cheaper anti-diabetic alternative that can act on multiple disease-related …

Background Diabetes mellitus is a global epidemic characterized by high morbidity and
mortality. Diabetes mellitus can lead to acute and chronic systemic complications. Among …

Functional hypogonadotropic hypogonadism (FHH) is an increasingly frequent condition,
whose pathological mechanisms are not yet fully clarified. The concept of FHH has now …