Glutathione: new roles in redox signaling for an old antioxidant

K Aquilano, S Baldelli, MR Ciriolo - Frontiers in pharmacology, 2014 - frontiersin.org
The physiological roles played by the tripeptide glutathione have greatly advanced over the
past decades superimposing the research on free radicals, oxidative stress and, more …

Oxidative stress in psychiatric disorders: evidence base and therapeutic implications

F Ng, M Berk, O Dean, AI Bush - International Journal of …, 2008 - academic.oup.com
Oxidative stress has been implicated in the pathogenesis of diverse disease states, and may
be a common pathogenic mechanism underlying many major psychiatric disorders, as the …

Real-time imaging of the intracellular glutathione redox potential

M Gutscher, AL Pauleau, L Marty, T Brach… - Nature …, 2008 - nature.com
Dynamic analysis of redox-based processes in living cells is now restricted by the lack of
appropriate redox biosensors. Conventional redox-sensitive GFPs (roGFPs) are limited by …

Oxidative stress and psychological disorders

S Salim - Current neuropharmacology, 2014 - ingentaconnect.com
Oxidative stress is an imbalance between cellular production of reactive oxygen species and
the counteracting antioxidant mechanisms. The brain with its high oxygen consumption and …

Environmental toxicity, oxidative stress and apoptosis: menage a trois

R Franco, R Sánchez-Olea, EM Reyes-Reyes… - … /Genetic Toxicology and …, 2009 - Elsevier
Apoptosis is an evolutionary conserved homeostatic process involved in distinct
physiological processes including organ and tissue morphogenesis, development and …

Oxidative stress in anxiety and comorbid disorders

I Hovatta, J Juhila, J Donner - Neuroscience research, 2010 - Elsevier
Anxiety disorders, depression, and alcohol use disorder are common neuropsychiatric
diseases that often occur together. Oxidative stress has been suggested to contribute to their …

Importance of iron chelation in free radical-induced oxidative stress and human disease

K Jomova, M Valko - Current pharmaceutical design, 2011 - ingentaconnect.com
Iron is a redox active metal involved in the oxidation-reduction reactions and regulation of
cell growth and differentiation. Iron is an integral part of many proteins and enzymes that …

Oxidative stress and ADHD: a meta-analysis

N Joseph, Y Zhang-James, A Perl… - Journal of attention …, 2015 - journals.sagepub.com
Objective: To clarify the role of oxidative stress and antioxidant activity in ADHD. Method: We
examined the association of ADHD and oxidative stress by applying random effects meta …

Molecular mechanisms of pesticide-induced neurotoxicity: Relevance to Parkinson's disease

R Franco, S Li, H Rodriguez-Rocha, M Burns… - Chemico-biological …, 2010 - Elsevier
Pesticides are widely used in agricultural and other settings, resulting in continued human
exposure. Pesticide toxicity has been clearly demonstrated to alter a variety of neurological …

Neuroendocrine, neuroinflammatory and pathological outcomes of chronic stress: A story of microglial remodeling

K Picard, MK St-Pierre, HA Vecchiarelli… - Neurochemistry …, 2021 - Elsevier
Microglia, the resident macrophage cells of the central nervous system (CNS), are involved
in a myriad of processes required to maintain CNS homeostasis. These cells are dynamic …