Hybrid nanosystems of antibiotics with metal nanoparticles—novel antibacterial agents

TI Shabatina, OI Vernaya, MY Melnikov - Molecules, 2023 - mdpi.com
The appearance and increasing number of microorganisms resistant to the action of
antibiotics is one of the global problems of the 21st century. Already, the duration of …

Metal Complexes as Antifungals? From a Crowd-Sourced Compound Library to the First In Vivo Experiments

A Frei, AG Elliott, A Kan, H Dinh, S Bräse, AE Bruce… - JACS au, 2022 - ACS Publications
There are currently fewer than 10 antifungal drugs in clinical development, but new fungal
strains that are resistant to most current antifungals are spreading rapidly across the world …

An overview on conventional and non-conventional therapeutic approaches for the treatment of candidiasis and underlying resistance mechanisms in clinical strains

SB Salazar, RS Simões, NA Pedro, MJ Pinheiro… - Journal of Fungi, 2020 - mdpi.com
Fungal infections and, in particular, those caused by species of the Candida genus, are
growing at an alarming rate and have high associated rates of mortality and morbidity …

Antifungal, Antitumoral and Antioxidant Potential of the Danube Delta Nymphaea alba Extracts

M Cudalbeanu, B Furdui, G Cârâc, V Barbu, AV Iancu… - Antibiotics, 2019 - mdpi.com
This study aimed to explore for the first time the biological properties such as antifungal,
antitumoral and antioxidant of Danube Delta Nymphaea alba (N. alba) leaf and root …

Conformational and Supramolecular Aspects in Chirality of Flexible Camphor-Containing Schiff Base as an Inducer of Helical Liquid Crystals

V Burmistrov, A Batrakova, V Aleksandriiskii, I Novikov… - Molecules, 2023 - mdpi.com
The experimental and theoretical study of influence of the conformational state and
association on the chirality of the stereochemically nonrigid biologically active bis …

On the path to gold: Monoanionic Au bisdithiolate complexes with antimicrobial and antitumor activities

SA Sousa, JH Leitão, RAL Silva, D Belo… - Journal of Inorganic …, 2020 - Elsevier
The emergence of resistance to antimicrobial and anticancer drugs poses severe threats to
public health worldwide, highlighting the need for more efficient treatments. Here, four …

[Ag(L)NO3] Complexes with 2-Benzoylpyridine-Derived Hydrazones: Cytotoxic Activity and Interaction with Biomolecules

AF Santos, IP Ferreira, CB Pinheiro, VG Santos… - ACS …, 2018 - ACS Publications
Complexes [Ag (H2BzPh) NO3](1),[Ag (H2Bz p CH3Ph) NO3](2),[Ag (H2Bz p ClPh) NO3](3),
and [Ag (H2Bz p NO2Ph) NO3](4) were synthesized with 2-benzoylpyridine …

Silver camphor imine complexes: novel antibacterial compounds from old medicines

JH Leitão, SA Sousa, SA Leite, MFNN Carvalho - Antibiotics, 2018 - mdpi.com
The emergence of bacterial resistance to available antimicrobials has prompted the search
for novel antibacterial compounds to overcome this public health problem. Metal-based …

Antimicrobial Activity of Silver Camphorimine Complexes against Candida Strains

JP Costa, MJF Pinheiro, SA Sousa… - Antibiotics, 2019 - mdpi.com
Hydroxide [Ag (OH) L](L= IVL, VL, VIL, VIIL), oxide [{AgL} 2}(μ-O)](L= IL, IIL, IIIL, VL, VIL) or
chloride [AgIIL] Cl,[Ag (VIL) 2] Cl complexes were obtained from reactions of mono-or …

[HTML][HTML] Insights into the Dual Anticancer and Antibacterial Activities of Composites Based on Silver Camphorimine Complexes

JP Costa, SA Sousa, JH Leitão, F Marques… - Journal of Functional …, 2024 - mdpi.com
Hydroxyapatite (HAp) is a widely used biocompatible material in orthopedic composite
preparations. However, HAp composites that exhibit both anticancer and antibacterial …