A great deal of information is known regarding the process of sex differentiation in fish, and
the mechanisms involved in primary sex determination are now beginning to be defined. A …

Cytochrome P450 (CYP) enzymes are members of the hemoprotein superfamily, and are
involved in the mono-oxygenation reactions of a wide range of endogenous and exogenous …

Zebrafish (Danio rerio) were exposed for 3 weeks to low concentrations of estradiol
including environmentally relevant concentrations (5, 25 and 100ng/l), encompassing either …

Steroid hormones modulate several important biological processes like metabolism, stress
response, and reproduction. Steroidogenesis drives reproductive function wherein …

Successful reproduction by an adult depends on the normal ontogenesis of the gonads, a
complex process of cellular and histological differentiation that starts early in life. This …

The abundant adrenal C19 steroid 11β-hydroxyandrostenedione (11OHA4) has been
written off as a dead-end product of adrenal steroidogenesis. However, recent evidence has …

Thyroid hormones (THs) are well-known regulators of development and metabolism in
vertebrates. There is increasing evidence that THs are also involved in gonadal …

Early differentiation in rainbow trout gonads was investigated by expression profiling and in
situ hybridization (ISH). Expression of cyp19a1 and fst in females and sox9a1 in males were …

The combined result of the mechanisms of sex determination and sex differentiation is the
sex ratio of a population. Because sex-related growth dimorphism in fish is quite common …

During gonadal differentiation of zebrafish, males temporarily develop a “juvenile ovary” that
is later degenerated and transformed into a testis (Takahashi, 1977; Maack and Segner …