Manipulating the destiny of wild populations using CRISPR
Genetic biocontrol aims to suppress or modify populations of species to protect public
health, agriculture, and biodiversity. Advancements in genome engineering technologies …
health, agriculture, and biodiversity. Advancements in genome engineering technologies …
Gene drive dynamics in natural populations: The importance of density dependence, space, and sex
The spread of synthetic gene drives is often discussed in the context of panmictic
populations connected by gene flow and described with simple deterministic models. Under …
populations connected by gene flow and described with simple deterministic models. Under …
Promises and perils of gene drives: Navigating the communication of complex, post-normal science
In November of 2017, an interdisciplinary panel discussed the complexities of gene drive
applications as part of the third Sackler Colloquium on “The Science of Science …
applications as part of the third Sackler Colloquium on “The Science of Science …
Does the US public support using gene drives in agriculture? And what do they want to know?
Gene drive development is progressing more rapidly than our understanding of public
values toward these technologies. We analyze a statistically representative survey (n= 1018) …
values toward these technologies. We analyze a statistically representative survey (n= 1018) …
Split versions of Cleave and Rescue selfish genetic elements for measured self limiting gene drive
Gene drive elements promote the spread of linked traits, providing methods for changing the
composition or fate of wild populations. Drive mechanisms that are self-limiting are attractive …
composition or fate of wild populations. Drive mechanisms that are self-limiting are attractive …
[HTML][HTML] Engagement on risk assessment for gene drive mosquitoes by EFSA and Target Malaria
S Hartley, A Kokotovich, Y Devos, J Mumford - Environmental Science & …, 2023 - Elsevier
As engineered gene drive technologies continue to advance, many actors are actively
considering how environmental risk assessments (RAs) for gene drive organisms should be …
considering how environmental risk assessments (RAs) for gene drive organisms should be …
Emerging technologies for invasive insects: the role of engagement
Emerging technologies have the potential to offer new applications for managing invasive
insects. While scientific and technological advancements are vital to realizing this potential …
insects. While scientific and technological advancements are vital to realizing this potential …
Seven open questions in the futures of human genome editing
Scholarly discussion around the governance of human genome editing (HGE) recognizes
that development and application of HGE techniques could result in unexpected societal …
that development and application of HGE techniques could result in unexpected societal …
Governing new biotechnologies for biodiversity conservation: gene drives, international law, and emerging politics
JL Reynolds - Global Environmental Politics, 2020 - direct.mit.edu
The outdoor use of organisms modified with gene drives—emerging biotechnologies of
biased inheritance—could further human well-being and biodiversity conservation, yet also …
biased inheritance—could further human well-being and biodiversity conservation, yet also …
Prescribing engagement in environmental risk assessment for gene drive technology
Gene drive technology is a nascent biotechnology with the potential to purposefully alter or
eliminate a species. There have been broad calls for engagement to inform gene drive …
eliminate a species. There have been broad calls for engagement to inform gene drive …