Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training

B Egan, AP Sharples - Physiological Reviews, 2023 - journals.physiology.org
Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

Physiological adaptations to low‐volume, high‐intensity interval training in health and disease

MJ Gibala, JP Little, MJ MacDonald… - The Journal of …, 2012 - Wiley Online Library
Exercise training is a clinically proven, cost‐effective, primary intervention that delays and in
many cases prevents the health burdens associated with many chronic diseases. However …

Short‐term sprint interval versus traditional endurance training: similar initial adaptations in human skeletal muscle and exercise performance

MJ Gibala, JP Little, M Van Essen… - The Journal of …, 2006 - Wiley Online Library
Brief, intense exercise training may induce metabolic and performance adaptations
comparable to traditional endurance training. However, no study has directly compared …

AMPK and the adaptation to exercise

HR Spaulding, Z Yan - Annual review of physiology, 2022 - annualreviews.org
Noncommunicable diseases are chronic diseases that contribute to death worldwide, but
these diseases can be prevented and mitigated with regular exercise. Exercise activates …

The molecular bases of training adaptation

VG Coffey, JA Hawley - Sports medicine, 2007 - Springer
Skeletal muscle is a malleable tissue capable of altering the type and amount of protein in
response to disruptions to cellular homeostasis. The process of exerciseinduced adaptation …

High-intensity aerobic interval training increases fat and carbohydrate metabolic capacities in human skeletal muscle

CGR Perry, GJF Heigenhauser… - Applied Physiology …, 2008 - cdnsciencepub.com
High-intensity aerobic interval training (HIIT) is a compromise between time-consuming
moderate-intensity training and sprint-interval training requiring all-out efforts. However …

Exercise training-induced regulation of mitochondrial quality

Z Yan, VA Lira, NP Greene - Exercise and sport sciences reviews, 2012 - journals.lww.com
Endurance exercise long has been recognized to not only enhance physical performance
but also bring about beneficial health outcomes. The most studied phenotypic adaptations in …

Skeletal muscle adaptation and performance responses to once a day versus twice every second day endurance training regimens

WK Yeo, CD Paton, AP Garnham… - Journal of Applied …, 2008 - journals.physiology.org
We determined the effects of a cycle training program in which selected sessions were
performed with low muscle glycogen content on training capacity and subsequent …

Matched work high-intensity interval and continuous running induce similar increases in PGC-1α mRNA, AMPK, p38, and p53 phosphorylation in human skeletal …

JD Bartlett, C Hwa Joo, TS Jeong… - Journal of applied …, 2012 - journals.physiology.org
The aim of the present study was to test the hypothesis that acute high-intensity interval (HIT)
running induces greater activation of signaling pathways associated with mitochondrial …

Six weeks of a polarized training-intensity distribution leads to greater physiological and performance adaptations than a threshold model in trained cyclists

CM Neal, AM Hunter, L Brennan… - Journal of applied …, 2013 - journals.physiology.org
This study was undertaken to investigate physiological adaptation with two endurance-
training periods differing in intensity distribution. In a randomized crossover fashion …