Automated chemical oligosaccharide synthesis: novel approach to traditional challenges
Advances in carbohydrate chemistry have certainly made common oligosaccharides much
more accessible. However, many current methods still rely heavily upon specialized …
more accessible. However, many current methods still rely heavily upon specialized …
Oligosaccharide synthesis and translational innovation
The translation of biological glycosylation in humans to the clinical applications involves
systematic studies using homogeneous samples of oligosaccharides and glycoconjugates …
systematic studies using homogeneous samples of oligosaccharides and glycoconjugates …
Stereocontrolled 1, 2-cis glycosylation as the driving force of progress in synthetic carbohydrate chemistry
Recent developments in stereoselective 1, 2-cis glycosylation that have emerged during the
past decade are surveyed herein. For detailed coverage of the previous achievements in the …
past decade are surveyed herein. For detailed coverage of the previous achievements in the …
Mechanisms of glycosylation reactions studied by low-temperature nuclear magnetic resonance
Synthesis of oligosaccharides has, for the past couple of decades, been greatly improved by
new methods and the ongoing development of new technologies, such as automation in …
new methods and the ongoing development of new technologies, such as automation in …
Merging Reagent Modulation and Remote Anchimeric Assistance for Glycosylation: Highly Stereoselective Synthesis of α‐Glycans up to a 30‐mer
Y Zhang, H He, Z Chen, Y Huang, G **ang… - Angewandte …, 2021 - Wiley Online Library
The efficient synthesis of long, branched, and complex carbohydrates containing multiple 1,
2‐cis glycosidic linkages is a long‐standing challenge. Here, we report a merging reagent …
2‐cis glycosidic linkages is a long‐standing challenge. Here, we report a merging reagent …
Boronic-Acid-Catalyzed Regioselective and 1,2-cis-Stereoselective Glycosylation of Unprotected Sugar Acceptors via SNi-Type Mechanism
M Tanaka, A Nakagawa, N Nishi, K Iijima… - Journal of the …, 2018 - ACS Publications
Regio-and 1, 2-cis-stereoselective chemical glycosylation of unprotected glycosyl acceptors
has been in great demand for the efficient synthesis of natural glycosides. However …
has been in great demand for the efficient synthesis of natural glycosides. However …
Reagent controlled stereoselective synthesis of α-glucans
L Wang, HS Overkleeft, GA van der Marel… - Journal of the …, 2018 - ACS Publications
The development of a general glycosylation method that allows for the stereoselective
construction of glycosidic linkages is a tremendous challenge. Because of the differences in …
construction of glycosidic linkages is a tremendous challenge. Because of the differences in …
Synthetically defined glycoprotein vaccines: current status and future directions
Primary examples in vaccine design have shown good levels of carbohydrate-specific
antibody generation when raised using extracted or fully synthetic capsular polysaccharide …
antibody generation when raised using extracted or fully synthetic capsular polysaccharide …
Recent Advances in Stereoselective Chemical O-Glycosylation Reactions
Carbohydrates involving glycoconjugates play a pivotal role in many life processes. Better
understanding toward glycobiological events including the structure–function relationship of …
understanding toward glycobiological events including the structure–function relationship of …
Regioselective and 1,2‐cis‐α‐Stereoselective Glycosylation Utilizing Glycosyl‐Acceptor‐Derived Boronic Ester Catalyst
A Nakagawa, M Tanaka, S Hanamura… - Angewandte …, 2015 - Wiley Online Library
Abstract Regioselective and 1, 2‐cis‐α‐stereoselective glycosylations using 1α, 2α‐anhydro
glycosyl donors and diol glycosyl acceptors in the presence of a glycosyl‐acceptor‐derived …
glycosyl donors and diol glycosyl acceptors in the presence of a glycosyl‐acceptor‐derived …