Primary structure of glycans by NMR spectroscopy
C Fontana, G Widmalm - Chemical Reviews, 2023 - ACS Publications
Glycans, carbohydrate molecules in the realm of biology, are present as biomedically
important glycoconjugates and a characteristic aspect is that their structures in many …
important glycoconjugates and a characteristic aspect is that their structures in many …
Methodology-centered review of molecular modeling, simulation, and prediction of SARS-CoV-2
Despite tremendous efforts in the past two years, our understanding of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), virus–host interactions, immune …
respiratory syndrome coronavirus 2 (SARS-CoV-2), virus–host interactions, immune …
Potential anti-SARS-CoV-2 activity of pentosan polysulfate and mucopolysaccharide polysulfate
With the increased prevalence of new SARS-CoV-2 variants of concern, such as Delta and
Omicron, the COVID-19 pandemic has become an ongoing human health disaster, killing …
Omicron, the COVID-19 pandemic has become an ongoing human health disaster, killing …
The diverse role of heparan sulfate and other GAGs in SARS-CoV-2 infections and therapeutics
In December 2019, the global coronavirus disease 2019 (COVID-19) pandemic began in
Wuhan, China. COVID-19 is caused by the severe acute respiratory syndrome coronavirus 2 …
Wuhan, China. COVID-19 is caused by the severe acute respiratory syndrome coronavirus 2 …
Antiviral activity of marine sulfated glycans against pathogenic human coronaviruses
Great interest exists towards the discovery and development of broad-spectrum antivirals.
This occurs due to the frequent emergence of new viruses which can also eventually lead to …
This occurs due to the frequent emergence of new viruses which can also eventually lead to …
Structure, anti-SARS-CoV-2, and anticoagulant effects of two sulfated galactans from the red alga Botryocladia occidentalis
The structure of the sulfated galactan from the red alga Botryocladia occidentalis (BoSG)
was originally proposed as a simple repeating disaccharide of alternating 4-linked α …
was originally proposed as a simple repeating disaccharide of alternating 4-linked α …
Structural characteristics of heparin binding to SARS-CoV-2 spike protein RBD of Omicron sub-lineages BA. 2.12. 1, BA. 4 and BA. 5
The now prevalent Omicron variant and its subvariants/sub-lineages have led to a significant
increase in COVID-19 cases and raised serious concerns about increased risk of infectivity …
increase in COVID-19 cases and raised serious concerns about increased risk of infectivity …
Anti-SARS-CoV-2 and anticoagulant properties of Pentacta pygmaea fucosylated chondroitin sulfate depend on high molecular weight structures
Fucosylated chondroitin sulfate (FucCS) is a unique marine glycosaminoglycan that exhibits
diverse biological functions, including antiviral and anticoagulant activity. In previous work …
diverse biological functions, including antiviral and anticoagulant activity. In previous work …
Inhibition of SARS-CoV-2 wild-type (Wuhan-Hu-1) and Delta (B. 1.617. 2) strains by marine sulfated glycans
The Coronavirus disease pandemic has steered the global therapeutic research efforts
toward the discovery of potential anti-severe acute respiratory syndrome coronavirus (SARS …
toward the discovery of potential anti-severe acute respiratory syndrome coronavirus (SARS …
Fractionation of sulfated galactan from the red alga Botryocladia occidentalis separates its anticoagulant and anti-SARS-CoV-2 properties
Sulfation pattern and molecular weight (MW) play a key role in the biological actions of
sulfated glycans. Besides anticoagulant effects, certain sulfated glycans can also exhibit anti …
sulfated glycans. Besides anticoagulant effects, certain sulfated glycans can also exhibit anti …