Biomarkers in stress related diseases/disorders: diagnostic, prognostic, and therapeutic values

K Dhama, SK Latheef, M Dadar, HA Samad… - Frontiers in molecular …, 2019 - frontiersin.org
Various internal and external factors negatively affect the homeostatic equilibrium of
organisms at the molecular to the whole-body level, inducing the so-called state of stress …

Biomarkers of acute kidney injury: the pathway from discovery to clinical adoption

K Kashani, W Cheungpasitporn… - Clinical Chemistry and …, 2017 - degruyter.com
Acute kidney injury (AKI) is a common complication of critical illnesses and has a significant
impact on outcomes, including mortality and morbidities. Unfortunately, apart from …

Disease detection with molecular biomarkers: from chemistry of body fluids to nature-inspired chemical sensors

YY Broza, X Zhou, M Yuan, D Qu, Y Zheng… - Chemical …, 2019 - ACS Publications
This article aims to review nature-inspired chemical sensors for enabling fast, relatively
inexpensive, and minimally (or non-) invasive diagnostics and follow-up of the health …

Long-term risk of CKD in children surviving episodes of acute kidney injury in the intensive care unit: a prospective cohort study

C Mammen, A Al Abbas, P Skippen, H Nadel… - American Journal of …, 2012 - Elsevier
BACKGROUND: The development of standardized acute kidney injury (AKI) definitions has
allowed for a better understanding of AKI epidemiology, but the long-term renal outcomes of …

Ultrabright fluorescent nanoscale labels for the femtomolar detection of analytes with standard bioassays

J Luan, A Seth, R Gupta, Z Wang, P Rathi… - Nature biomedical …, 2020 - nature.com
The detection and quantification of low-abundance molecular biomarkers in biological
samples is challenging. Here, we show that a plasmonic nanoscale construct serving as an …

Recent progress in fluorescent molecular systems for the detection of disease-related biomarkers in biofluids

RR Nair, JM An, J Kim, D Kim - Coordination Chemistry Reviews, 2023 - Elsevier
The use of biofluids as a diagnostic tool for chronic health conditions has been gaining
traction in recent years. These fluids, which can be obtained non-invasively (such as urine …

Renal failure in cirrhosis

P Ginès, RW Schrier - New England Journal of Medicine, 2009 - Mass Medical Soc
Renal failure, a challenging complication of cirrhosis, is one of the most important risk factors
for liver transplantation. In recent years, substantial progress has been made toward …

Sensitivity and specificity of a single emergency department measurement of urinary neutrophil gelatinase–associated lipocalin for diagnosing acute kidney injury

TL Nickolas, MJ O'Rourke, J Yang, ME Sise… - Annals of internal …, 2008 - acpjournals.org
Background: A single serum creatinine measurement cannot distinguish acute kidney injury
from chronic kidney disease or prerenal azotemia. Objective: To test the sensitivity and …

Kidney injury molecule-1 (KIM-1): a urinary biomarker and much more

JV Bonventre - Nephrology Dialysis Transplantation, 2009 - academic.oup.com
6. Jain AK, McLeod I, Huo C et al. When laboratories report estimated glomerular filtration
rates in addition to serum creatinines, nephrology consults increase. Kidney Int 2009 May 13 …

Diagnosis, epidemiology and outcomes of acute kidney injury

SS Waikar, KD Liu, GM Chertow - Clinical Journal of the American …, 2008 - journals.lww.com
Acute kidney injury is an increasingly common and potentially catastrophic complication in
hospitalized patients. Early observational studies from the 1980s and 1990s established the …