Understanding the mechanisms and treatments of long COVID to address future public health risks
B Li, J Bai, Y **ong, D Guo, B Fu, G Deng, H Wu - Life Sciences, 2024 - Elsevier
Abstract The 2019 coronavirus disease (COVID-19), triggered by the severe acute
respiratory syndrome coronavirus (SARS-CoV-2), has seen numerous individuals undergo …
respiratory syndrome coronavirus (SARS-CoV-2), has seen numerous individuals undergo …
Nsp1 proteins of human coronaviruses HCoV-OC43 and SARS-CoV2 inhibit stress granule formation
SM Dolliver, M Kleer, MP Bui-Marinos, S Ying… - PLoS …, 2022 - journals.plos.org
Stress granules (SGs) are cytoplasmic condensates that often form as part of the cellular
antiviral response. Despite the growing interest in understanding the interplay between SGs …
antiviral response. Despite the growing interest in understanding the interplay between SGs …
Structural basis for translation inhibition by MERS-CoV Nsp1 reveals a conserved mechanism for betacoronaviruses
All betacoronaviruses (β-CoVs) encode non-structural protein 1 (Nsp1), an essential
pathogenicity factor that potently restricts host gene expression. Among the β-CoV family …
pathogenicity factor that potently restricts host gene expression. Among the β-CoV family …
An evolutionarily conserved strategy for ribosome binding and host translation inhibition by β-coronavirus non-structural protein 1
SF Maurina, JP O'Sullivan, G Sharma… - Journal of molecular …, 2023 - Elsevier
An important pathogenicity factor of SARS-CoV-2 and related coronaviruses is Non-
structural protein 1 (Nsp1), which suppresses host gene expression and stunts antiviral …
structural protein 1 (Nsp1), which suppresses host gene expression and stunts antiviral …
MERS-CoV nsp1 regulates autophagic flux via mTOR signalling and dysfunctional lysosomes
Y Feng, Z Pan, Z Wang, Z Lei, S Yang… - Emerging Microbes & …, 2022 - Taylor & Francis
Autophagy, a cellular surveillance mechanism, plays an important role in combating
invading pathogens. However, viruses have evolved various strategies to disrupt autophagy …
invading pathogens. However, viruses have evolved various strategies to disrupt autophagy …
The involvement of endogenous melatonin in LPS-induced M1-like macrophages and its underlying synthesis mechanism regulated by IRF3
X Chen, Z Zhang, H Huang, Y Deng, Z Xu… - Experimental Cell …, 2024 - Elsevier
Melatonin (MLT) has been shown to induce polarization of macrophages towards M2-like
phenotype and inhibit polarization of macrophages towards M1-like phenotype through …
phenotype and inhibit polarization of macrophages towards M1-like phenotype through …
[PDF][PDF] The 82 GHVMV and 141 KSF deletions in the Nsp1 protein of ORF1ab polyprotein favour the creation of immune-weak SARS-CoV-2
AK Chakraborty - SunText Rev Virol, 2023 - suntextreviews.org
The Wuhan corona virus was mutated and deleted at different positions of the genome
specifically in deadly Alpha and Delta variants whereas spike protein was mostly affected in …
specifically in deadly Alpha and Delta variants whereas spike protein was mostly affected in …
PSMD12 promotes non-small cell lung cancer progression through activating the Nrf2/TrxR1 pathway
J Lv, S Ma, X Wang, J Dang, F Ma - Genes & Genomics, 2024 - Springer
Background Non-small cell lung cancer (NSCLC) contributes to the vast majority of cancer-
related deaths. Proteasome 26S subunit, non-ATPase 12 (PSMD12), a subunit of 26S …
related deaths. Proteasome 26S subunit, non-ATPase 12 (PSMD12), a subunit of 26S …
An evolutionarily conserved strategy for ribosome binding and inhibition by β-coronavirus non-structural protein 1
SF Maurina, JP O'Sullivan, G Sharma… - …, 2023 - pmc.ncbi.nlm.nih.gov
An important pathogenicity factor of SARS-CoV-2 and related coronaviruses is Nsp1, which
suppresses host gene expression and stunts antiviral signaling. SARS-CoV-2 Nsp1 binds …
suppresses host gene expression and stunts antiviral signaling. SARS-CoV-2 Nsp1 binds …
Uncovering strain-and age-dependent differences in innate immune response to SARS-CoV-2 infection in nasal epithelia using combined short and long-read scRNA …
Assessing the impact of SARS-CoV-2 variants on host immune systems is crucial with the
continuous arrival of novel variants. However, there is a lack of reported studies utilizing …
continuous arrival of novel variants. However, there is a lack of reported studies utilizing …