Cognitive impairment in schizophrenia: aetiology, pathophysiology, and treatment

RA McCutcheon, RSE Keefe, PK McGuire - Molecular psychiatry, 2023 - nature.com
Cognitive deficits are a core feature of schizophrenia, account for much of the impaired
functioning associated with the disorder and are not responsive to existing treatments. In this …

[HTML][HTML] Tensor decomposition of EEG signals: a brief review

F Cong, QH Lin, LD Kuang, XF Gong… - Journal of neuroscience …, 2015 - Elsevier
Electroencephalography (EEG) is one fundamental tool for functional brain imaging. EEG
signals tend to be represented by a vector or a matrix to facilitate data processing and …

Visual mismatch negativity: a predictive coding view

G Stefanics, J Kremláček, I Czigler - Frontiers in human neuroscience, 2014 - frontiersin.org
An increasing number of studies investigate the visual mismatch negativity (vMMN) or use
the vMMN as a tool to probe various aspects of human cognition. This paper reviews the …

Therapeutic potential of TAAR1 agonists in schizophrenia: evidence from preclinical models and clinical studies

N Dedic, H Dworak, C Zeni, G Rutigliano… - International Journal of …, 2021 - mdpi.com
Trace amine-associated receptor 1 (TAAR1) has emerged as a promising therapeutic target
for neuropsychiatric disorders due to its ability to modulate monoaminergic and …

Learning-induced neural plasticity of speech processing before birth

E Partanen, T Kujala, R Näätänen, A Liitola… - Proceedings of the …, 2013 - pnas.org
Learning, the foundation of adaptive and intelligent behavior, is based on plastic changes in
neural assemblies, reflected by the modulation of electric brain responses. In infancy …

The mismatch negativity (MMN)–a unique window to disturbed central auditory processing in ageing and different clinical conditions

R Näätänen, T Kujala, C Escera, T Baldeweg… - Clinical …, 2012 - Elsevier
In this article, we review clinical research using the mismatch negativity (MMN), a change-
detection response of the brain elicited even in the absence of attention or behavioural task …

Sensory processing in autism spectrum disorders and Fragile X syndrome—From the clinic to animal models

D Sinclair, B Oranje, KA Razak, SJ Siegel… - … & Biobehavioral Reviews, 2017 - Elsevier
Brains are constantly flooded with sensory information that needs to be filtered at the pre-
attentional level and integrated into endogenous activity in order to allow for detection of …

Developments in scalable strategies for detecting early markers of cognitive decline

R Whelan, FM Barbey, MR Cominetti, CM Gillan… - Translational …, 2022 - nature.com
Effective strategies for early detection of cognitive decline, if deployed on a large scale,
would have individual and societal benefits. However, current detection methods are …

Mismatch negativity (MMN) as an index of cognitive dysfunction

R Näätänen, ES Sussman, D Salisbury, VL Shafer - Brain topography, 2014 - Springer
Cognition is often affected in a variety of neuropsychiatric, neurological, and
neurodevelopmental disorders. The neural discriminative response, reflected in mismatch …

[HTML][HTML] Stratified medicine for mental disorders

G Schumann, EB Binder, A Holte, ER de Kloet… - European …, 2014 - Elsevier
There is recognition that biomedical research into the causes of mental disorders and their
treatment needs to adopt new approaches to research. Novel biomedical techniques have …