The fruit fly, Drosophila melanogaster, has helped us to understand how innate immunity is
activated. In addition to the Toll receptor and the Toll signaling pathway, the Drosophila …

Crustacean hemocytes are important mediators of immune reactions, and the regulation of
hemocyte homeostasis is of utmost importance for the health of these animals. This review …

Loss-of-function mutations in the histone demethylases KDM5A, KDM5B, or KDM5C are
found in intellectual disability (ID) and autism spectrum disorders (ASD) patients. Here, we …

Microbe-derived acetate activates the Drosophila immunodeficiency (IMD) pathway in a
subset of enteroendocrine cells (EECs) of the anterior midgut. In these cells, the IMD …

Antiviral immunity in Drosophila involves RNA interference and poorly characterized
inducible responses. Here, we showed that two components of the IMD pathway, the kinase …

The specification and adaptability of cells rely on changes in protein composition.
Nonetheless, uncovering proteome dynamics with cell-type-specific resolution remains …

The network of NF‐κB‐dependent transcription that activates both pro‐and anti‐
inflammatory genes in mammals is still unclear. As NF‐κB factors are evolutionarily …

Metazoans have developed strategies to protect themselves from pathogenic attack. These
preserved mechanisms constitute the immune system, composed of innate and adaptive …

Yellow mealworm (Tenebrio molitor) is a highly beneficial beetle that serves as an excellent
source of edible protein as well as a practical study model. Therefore, studying its immune …

Insects depend on the innate immune response for defense against a wide array of
pathogens. Central to Drosophila immunity are antimicrobial peptides (AMPs), released into …