[HTML][HTML] Advances in research on bioactivity, toxicity, metabolism, and pharmacokinetics of usnic acid in vitro and in vivo

H Wang, M Xuan, C Huang, C Wang - Molecules, 2022 - mdpi.com
Lichens are among the most widely distributed plants on earth and have the longest growth
cycle. Usnic acid is an abundant characteristic secondary metabolite of lichens and the …

The metabolomic window into hepatobiliary disease

D Beyoğlu, JR Idle - Journal of hepatology, 2013 - Elsevier
The emergent discipline of metabolomics has attracted considerable research effort in
hepatology. Here we review the metabolomic data for non-alcoholic fatty liver disease …

[HTML][HTML] Protective Effects of Naringenin from Citrus sinensis (var. Valencia) Peels against CCl4-Induced Hepatic and Renal Injuries in Rats Assessed by …

NM Ammar, HA Hassan, HMI Abdallah, SM Afifi… - Nutrients, 2022 - mdpi.com
Citrus fruits are grown worldwide for their special nutritive and several health benefits.
Among citrus bioactives, naringenin, a major flavanone, exhibits a potential hepatoprotective …

Enantioselective activity of usnic acid: A comprehensive review and future perspectives

A Galanty, P Paśko, I Podolak - Phytochemistry Reviews, 2019 - Springer
This review is focused on the comparison of the biological and pharmacological activities of
usnic acid enantiomers. Most of the available data refer to (+)-usnic acid, while the left …

Lipidomic profiling study on neurobehavior toxicity in zebrafish treated with aflatoxin B1

Z Wang, X Li, T Wang, G Liao, J Gu, R Hou… - Science of The Total …, 2023 - Elsevier
Abstract Mycotoxin aflatoxin B1 (AFB1) has been proven to cause neurotoxicity, but its
potential interference with the normal function of brain tissue is not fully defined. As the …

[HTML][HTML] Neuroprotective effects of Ginkgo biloba drop** pills in Parkinson's disease

D Yu, P Zhang, J Li, T Liu, Y Zhang, Q Wang… - Journal of …, 2021 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disease in the
world; however, it lacks effective and safe treatments. Ginkgo biloba drop** pill (GBDP), a …

Usnic acid: From an ancient lichen derivative to promising biological and nanotechnology applications

DCS Macedo, FJF Almeida, MSO Wanderley… - Phytochemistry …, 2021 - Springer
Among the various compounds of natural origin, usnic acid (UA) is one of the best studied. It
has several pharmacological activities, standing out as an antimicrobial, antitumor, antiviral …

Integrated analysis of transcriptomics and metabonomics profiles in aflatoxin B1-induced hepatotoxicity in rat

X Lu, B Hu, L Shao, Y Tian, T **, Y **, S Ji… - Food and chemical …, 2013 - Elsevier
The aim of this work was to identify mechanisms and potential biomarkers for predicting the
development and progression of aflatoxin B1 (AFB1)-induced acute hepatotoxicity. In this …

Protective effects of curcumin against aflatoxicosis: A comprehensive review

M Mohajeri, B Behnam, AFG Cicero… - Journal of cellular …, 2018 - Wiley Online Library
Aflatoxicosis is a deleterious medical condition that results from aflatoxins (AFs) or
ochratoxins (OTs). Contamination with these toxins exerts detrimental effects on the liver …

[HTML][HTML] Permeability of Hypogymnia physodes Extract Component—Physodic Acid through the Blood–Brain Barrier as an Important Argument for Its Anticancer and …

E Studzińska-Sroka, A Majchrzak-Celińska, P Zalewski… - Cancers, 2021 - mdpi.com
Simple Summary Central nervous system (CNS) diseases, including tumors such as
glioblastomas and neurodegenerative diseases, such as Alzheimer's disease, are some of …