Mitochondria are best known for harboring pathways involved in ATP synthesis through the
tricarboxylic acid cycle and oxidative phosphorylation. Major advances in understanding …

Mitochondrial dynamics are regulated by two sets of opposed processes: mitochondrial
fusion and fission, and mitochondrial biogenesis and degradation (including mitophagy), as …

Cadmium (Cd) is a poisonous metal element that causes mitochondrial dysfunction.
Selenium (Se) can reduce the damage of Cd to various organs of animals, but the protective …

Recent decades have seen a rapid increase in reported toxic effects of drugs and pollutants
on mitochondria. Researchers have also documented many genetic differences leading to …

Caenorhabditis elegans has emerged as a major model in biomedical and environmental
toxicology. Numerous papers on toxicology and pharmacology in C. elegans have been …

The long noncoding RNA NEAT1 (nuclear enriched abundant transcript 1) nucleates the
formation of paraspeckles, which constitute a type of nuclear body with multiple roles in …

Due to many advantages Caenorhabditis elegans (C. elegans) has become a preferred
model of choice in many fields, including neurodevelopmental toxicity studies. This review …

Arsenic (As) is a ubiquitous environmental toxin and robust inducer of oxidative stress (OxS).
Copper (Cu) is an essential microelement, which participates in OxS as a cofactor for certain …

Ever increasing environmental presence of cadmium as a consequence of industrial
activities is considered a health hazard and is closely linked to deteriorating global health …

Paraquat (methyl viologen), is a non-selective contact herbicide and well known
mitochondrial toxicant. Mitochondria are the center of cellular metabolism, and involved in …