Mature microRNAs (miRNAs) are a class of evolutionally conserved, single-stranded, small
(approximately 19− 23 nucleotides), endogenously expressed, and non-protein-coding …

MicroRNAs (miRNAs) are a recently discovered class of small, non-coding RNAs that
regulate protein levels post-transcriptionally. miRNAs play important regulatory roles in …

In this work, a label-free and highly sensitive fluorescence assay was constructed for
microRNA detection. Nicking-enhanced rolling circle amplification (RCA) induced by G …

The volume of point of care (POC) testing continues to grow steadily due to the increased
availability of easy-to-use devices, thus making it possible to deliver less costly care closer …

A nanomotor-based strategy for rapid single-step intracellular biosensing of a target miRNA,
expressed in intact cancer cells, at the single cell level is described. The new concept relies …

MicroRNAs are a class of small non-coding RNAs that serve as important regulators of gene
expression at the posttranscriptional level. They are stable in body fluids and pose great …

Through rational design of a functional molecular probe with high sequence specificity that
takes advantage of sensitive isothermal amplification with simple operation, we developed a …

MicroRNAs are short noncoding RNAs consisting of 18–25 nucleotides that target specific
mRNA moieties for translational repression or degradation, thereby modulating numerous …

Nonenzymatic nucleic acid amplification techniques (eg the hybridization chain reaction,
HCR) have shown promising potential for amplified detection of biomarkers. However, the …

Early detection is proven to be the best chance for successful cancer treatment. MiRNAs, as
ideal biomarkers, can identify cancer in the early stage. Therefore, development of highly …