Following their discovery over 50 years ago, mesenchymal stromal cells (MSCs) have
become one of the most studied cellular therapeutic products by both academia and industry …

The role of native (not culture-expanded) joint-resident mesenchymal stem cells (MSCs) in
the repair of joint damage in osteoarthritis (OA) is poorly understood. MSCs differ from bone …

Mesenchymal stromal cells (MSCs) are currently being investigated in numerous clinical
trials of tissue repair and various immunological disorders based on their ability to secrete …

Studies to evaluate the therapeutic potential of stem cells in humans would benefit from
more realistic animal models. In veterinary medicine, companion animals naturally develop …

Keratoconjunctivitis sicca (KCS) or dry eye disease (DED) is an immune‐mediated
multifactorial disease, with high level of prevalence in humans and dogs. Our aim in this …

Veterinary adult stem cell therapy is an emerging area of basic and clinical research. Like
their human counterparts, veterinary mesenchymal stem cells (MSCs) offer many potential …

Abstract Background Mesenchymal stem cells (MSCs) transplantation has become a
promising therapeutic choice for musculoskeletal injuries. Joint-related disorders are highly …

Objective: The primary objective of this study was to identify adverse events associated with
multiple intra-articular injections of adipose stromal cell (ASC) therapy and secondarily to …

Background The ability of mesenchymal stem cells (MSCs) to modulate immune responses
inspired a series of clinical trials addressing oral mucosal inflammation. We previously …

Articular cartilage damaged through trauma or disease has a limited ability to repair.
Untreated, focal lesions progress to generalized changes including osteoarthritis …