Intracellular membrane traffic defines a complex network of pathways that connects many of
the membrane-bound organelles of eukaryotic cells. Although each pathway is governed by …

The organization of cells into interconnected structures such as animal tissues requires a
sophisticated system directing receptors and adhesion proteins to the cell surface. The …

Small GTPases of the rab family are crucial elements of the machinery that controls
membrane traffic. In the present study, we examined the distribution and function of rab11 …

Two endosome populations involved in recycling of membranes and receptors to the plasma
membrane have been described, the early and the recycling endosome. However, this …

Vesicular/membrane trafficking essentially regulates the compartmentalization and
abundance of proteins within the cells and contributes in many signalling pathways. This …

Multivesicular bodies (MVBs) are membranous structures within 60–100 nm diameter
vesicles accumulate. MVBs are generated after invagination and pinching off of the …

During maturation, reticulocytes lose some membrane proteins that are not required on the
mature red cell surface. The proteins are released into the extracellular medium associated …

Receptor-mediated endocytosis is known to play an important role in the entry of many
viruses into host cells. However, the exact internalization mechanism has, until recently …

Rab11 is a small GTP-binding protein that in cultured mammalian cells has been shown to
be concentrated in the pericentriolar endosomal recycling compartment and to play a key …

The rab11 GTPase has been localized to both the Golgi and recycling endosomes; however,
its Golgi-associated function has remained obscure. In this study, rab11 function in exocytic …