Macrophage inflammatory protein-1
P Menten, A Wuyts, J Van Damme - Cytokine & growth factor reviews, 2002 - Elsevier
Macrophage inflammatory protein-1α (MIP-1α) and MIP-1β are highly related members of
the CC chemokine subfamily. Despite their structural similarities, MIP-1α and MIP-1β show …
the CC chemokine subfamily. Despite their structural similarities, MIP-1α and MIP-1β show …
Structure, function, and inhibition of chemokines
Chemokines are the largest family of cytokines in human immunophysiology. These proteins
are defined by four invariant cysteines and are categorized based on the sequence around …
are defined by four invariant cysteines and are categorized based on the sequence around …
New paradigms in chemokine receptor signal transduction: Moving beyond the two-site model
Chemokine receptor (CKR) signaling forms the basis of essential immune cellular functions,
and dysregulated CKR signaling underpins numerous disease processes of the immune …
and dysregulated CKR signaling underpins numerous disease processes of the immune …
[HTML][HTML] NF-κB/MAPK activation underlies ACVR1-mediated inflammation in human heterotopic ossification
BACKGROUND. Inflammation helps regulate normal growth and tissue repair. Although
bone morphogenetic proteins (BMPs) and inflammation are known contributors to abnormal …
bone morphogenetic proteins (BMPs) and inflammation are known contributors to abnormal …
Tyrosine sulfation: an increasingly recognised post-translational modification of secreted proteins
The post-translational sulfation of tyrosine residues occurs in numerous secreted and
integral membrane proteins and, in many cases, plays a crucial role in controlling the …
integral membrane proteins and, in many cases, plays a crucial role in controlling the …
Structural basis of chemokine receptor function—a model for binding affinity and ligand selectivity
L Rajagopalan, K Rajarathnam - Bioscience reports, 2006 - portlandpress.com
Chemokine receptors play fundamental roles in human physiology from embryogenesis to
inflammatory response. The receptors belong to the G-protein coupled receptor class, and …
inflammatory response. The receptors belong to the G-protein coupled receptor class, and …
The structural role of receptor tyrosine sulfation in chemokine recognition
JP Ludeman, MJ Stone - British journal of pharmacology, 2014 - Wiley Online Library
Tyrosine sulfation is a post‐translational modification of secreted and transmembrane
proteins, including many GPCRs such as chemokine receptors. Most chemokine receptors …
proteins, including many GPCRs such as chemokine receptors. Most chemokine receptors …
Structural basis of chemokine and receptor interactions: Key regulators of leukocyte recruitment in inflammatory responses
In response to infection or injury, the body mounts an inflammatory immune response in
order to neutralize pathogens and promote tissue repair. The key effector cells for these …
order to neutralize pathogens and promote tissue repair. The key effector cells for these …
Eosinophils in inflammatory bowel disease
RT Filippone, L Sahakian… - Inflammatory bowel …, 2019 - academic.oup.com
Clinical investigations in inflammatory bowel disease (IBD) patients have provided
increasing evidence that eosinophils contribute to chronic intestinal inflammation …
increasing evidence that eosinophils contribute to chronic intestinal inflammation …
CCL11, a novel mediator of inflammatory bone resorption
E Kindstedt, CK Holm, R Sulniute… - Scientific reports, 2017 - nature.com
Normal bone homeostasis, which is regulated by bone-resorbing osteoclasts and bone-
forming osteoblasts is perturbed by inflammation. In chronic inflammatory disease with …
forming osteoblasts is perturbed by inflammation. In chronic inflammatory disease with …