Chloroquine is a 9-aminoquinoline known since 1934. Apart from its well-known antimalarial
effects, the drug has interesting biochemical properties that might be applied against some …

Synthetic oligodeoxynucleotides (ODNs) that contain immunostimulatory CpG motifs trigger
an immunomodulatory cascade that involves B and T cells, natural killer cells and …

The causes of the recent reemergence of Plasmodium falciparum epidemic malaria in the
East African highlands are controversial. Regional climate changes have been invoked as a …

Measuring tuberculosis transmission is exceedingly difficult, given the remarkable variability
in the timing of clinical disease after Mycobacterium tuberculosis infection; incident disease …

The incidence of tuberculosis (TB) is currently increasing in HIV-infected patients living in
Africa and Asia, where TB endemicity is high, reflecting the susceptibility of this group of …

Sexually transmitted infections (STIs) constitute a huge health and economic burden for
develo** countries: 75–85% of the estimated 340 million annual new cases of curable …

[Publisher-supplied data] Relatively few people have access to antiretroviral treatment in
South Africa. The government justifies this on grounds of affordability. Nicoli Nattrass argues …

In sub-Saharan Africa, human immunodeficiency virus (HIV) and malaria are among the
leading causes of morbidity during pregnancy. We reviewed available information collected …

Anautogeny is a successful reproductive strategy utilized by many mosquito species and
other disease-transmitting arthropod vectors. Develo** an understanding of the …

A high burden of malaria, tuberculosis, and HIV infection contributes to national and
individual poverty. We have reviewed a broad range of evidence detailing factors at …