The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …

Antibiotic-mediated perturbation of the gut microbiome is associated with numerous
infectious and autoimmune diseases of the gastrointestinal tract. Yet, as the gut microbiome …

The human microbiome influences the efficacy and safety of a wide variety of commonly
prescribed drugs. Designing precision medicine approaches that incorporate microbial …

The gut microbiome is associated with diverse diseases,–, but a universal signature of a
healthy or unhealthy microbiome has not been identified, and there is a need to understand …

A large body of evidence has emerged in the past decade supporting a role for the gut
microbiome in the regulation of blood pressure. The field has moved from association to …

The 1013–1014 microorganisms present in the human gut (collectively known as the human
gut microbiota) dedicate substantial percentages of their genomes to the degradation and …

Evidence for a close bidirectional link between the brain and the gut has led to a paradigm
shift in neurology, especially in the case of Parkinson disease (PD), in which gastrointestinal …

Growing evidence suggests that the gut microbiota modulates the efficacy and toxicity of
cancer therapy, most notably immunotherapy and its immune-related adverse effects. The …

The gut–liver axis plays a prominent role in the pathogenesis and therapy of metabolic
diseases such as diabetes. The intestinal specific origin of several hormones that guide both …

Emerging evidence indicates that gut microbiota is important in the regulation of brain
activity and cognitive functions. Microbes mediate communication among the metabolic …