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Physiology and pathophysiology of purinergic neurotransmission
G Burnstock - Physiological reviews, 2007 - journals.physiology.org
This review is focused on purinergic neurotransmission, ie, ATP released from nerves as a
transmitter or cotransmitter to act as an extracellular signaling molecule on both pre-and …
transmitter or cotransmitter to act as an extracellular signaling molecule on both pre-and …
[HTML][HTML] Adenosine receptors and brain diseases: neuroprotection and neurodegeneration
Adenosine acts in parallel as a neuromodulator and as a homeostatic modulator in the
central nervous system. Its neuromodulatory role relies on a balanced activation of inhibitory …
central nervous system. Its neuromodulatory role relies on a balanced activation of inhibitory …
Dopamine D2 receptors in discrimination learning and spine enlargement
Abstract Dopamine D2 receptors (D2Rs) are densely expressed in the striatum and have
been linked to neuropsychiatric disorders such as schizophrenia,. High-affinity binding of …
been linked to neuropsychiatric disorders such as schizophrenia,. High-affinity binding of …
Detection of Heteromers Formed by Cannabinoid CB1, Dopamine D2, and Adenosine A2A G‐Protein‐Coupled Receptors by Combining Bimolecular Fluorescence …
Functional interactions in signaling occur between dopamine D2 (D2R) and cannabinoid
CB1 (CB1R) receptors, between CB1R and adenosine A2A (A2AR) receptors, and between …
CB1 (CB1R) receptors, between CB1R and adenosine A2A (A2AR) receptors, and between …
The discovery of central monoamine neurons gave volume transmission to the wired brain
K Fuxe, AB Dahlström, G Jonsson, D Marcellino… - Progress in …, 2010 - Elsevier
The dawn of chemical neuroanatomy in the CNS came with the discovery and map** of
the central dopamine, noradrenaline and 5-hydroxytryptamine neurons by means of …
the central dopamine, noradrenaline and 5-hydroxytryptamine neurons by means of …
Dopamine, behavioral economics, and effort
There are numerous problems with the hypothesis that brain dopamine (DA) systems,
particularly in the nucleus accumbens, directly mediate the rewarding or primary …
particularly in the nucleus accumbens, directly mediate the rewarding or primary …
Detection of antigen interactions ex vivo by proximity ligation assay: endogenous dopamine D2-adenosine A2A receptor complexes in the striatum
P Trifilieff, ML Rives, E Urizar, RA Piskorowski… - …, 2011 - Taylor & Francis
The existence of G protein-coupled receptor (GPCR) dimers and/or oligomers has been
demonstrated in heterologous systems using a variety of biochemical and biophysical …
demonstrated in heterologous systems using a variety of biochemical and biophysical …
Metabotropic glutamate type 5, dopamine D2 and adenosine A2a receptors form higher‐order oligomers in living cells
N Cabello, J Gandía, DCG Bertarelli… - Journal of …, 2009 - Wiley Online Library
G protein‐coupled receptors are known to form homo‐and heteromers at the plasma
membrane, but the stoichiometry of these receptor oligomers are relatively unknown. Here …
membrane, but the stoichiometry of these receptor oligomers are relatively unknown. Here …
Heterodimerization of g protein-coupled receptors: specificity and functional significance
G protein-coupled receptors (GPCRs) are cell surface receptors that mediate physiological
responses to a diverse array of stimuli. GPCRs have traditionally been thought to act as …
responses to a diverse array of stimuli. GPCRs have traditionally been thought to act as …
Dopaminergic modulation of effort-related choice behavior as assessed by a progressive ratio chow feeding choice task: pharmacological studies and the role of …
Mesolimbic dopamine (DA) is involved in behavioral activation and effort-related processes.
Rats with impaired DA transmission reallocate their instrumental behavior away from food …
Rats with impaired DA transmission reallocate their instrumental behavior away from food …