Ionic liquids: new forms of active pharmaceutical ingredients with unique, tunable properties

JL Shamshina, RD Rogers - Chemical Reviews, 2023 - ACS Publications
This Review aims to summarize advances over the last 15 years in the development of
active pharmaceutical ingredient ionic liquids (API-ILs), which make up a prospective game …

Multifunctional nanoparticle-mediated combining therapy for human diseases

X Li, X Peng, M Zoulikha, GF Boafo, KT Magar… - … and Targeted Therapy, 2024 - nature.com
Combining existing drug therapy is essential in develo** new therapeutic agents in
disease prevention and treatment. In preclinical investigations, combined effect of certain …

Unearthing Superior Inorganic UV Second‐Order Nonlinear Optical Materials: A Mineral‐Inspired Method Integrating First‐Principles High‐Throughput Screening and …

X Dong, H Huang, L Huang, Y Zhou… - Angewandte Chemie …, 2024 - Wiley Online Library
Natural minerals, with their adaptable framework structures exemplified by perovskite and
lyonsite, have sparked substantial interest as potential templates for the design of advanced …

Deep eutectic solvents enhancing drug solubility and its delivery

A Sharma, YR Park, A Garg, BS Lee - Journal of Medicinal …, 2024 - ACS Publications
Deep eutectic solvents (DES) are environmentally friendly solvents with the potential to
dissolve bioactive compounds without affecting their characteristics. DES has special …

Diffusion and Flux Improvement of Drugs through Complexation

MKC Mannava, A Garai, AK Nangia - Molecular Pharmaceutics, 2023 - ACS Publications
Improving the solubility and permeability of drugs via cocrystallization is an important theme
in crystal engineering with practical applications for the discovery and development of high …

Modulating the electromechanical response of bio-inspired amino acid-based architectures through supramolecular co-assembly

W Ji, B Xue, Y Yin, S Guerin, Y Wang… - Journal of the …, 2022 - ACS Publications
Supramolecular packing dictates the physical properties of bio-inspired molecular
assemblies in the solid state. Yet, modulating the stacking modes of bio-inspired …

Pursuing Green and Efficient Agriculture from Molecular Assembly: A Review of Solid-State Forms on Agrochemicals

Y **ao, C Wu, P Cui, L Zhou, Q Yin - Journal of Agricultural and …, 2023 - ACS Publications
Achieving rapid global agricultural development while maintaining ecological harmony is a
major challenge of the new millennium. Meeting this challenge requires the development of …

The relevance of crystal forms in the pharmaceutical field: sword of damocles or innovation tools?

D Braga, L Casali, F Grepioni - International Journal of Molecular …, 2022 - mdpi.com
This review is aimed to provide to an “educated but non-expert” readership and an overview
of the scientific, commercial, and ethical importance of investigating the crystalline forms …

[HTML][HTML] Solubilization techniques used for poorly water-soluble drugs

B **e, Y Liu, X Li, P Yang, W He - Acta Pharmaceutica Sinica B, 2024 - Elsevier
Currently, about 40% of approved drugs and nearly 90% of drug candidates are poorly
water-soluble drugs. Low solubility reduces the likelihood that these drugs can be effectively …

Crystal engineering: from promise to delivery

D Braga - Chemical Communications, 2023 - pubs.rsc.org
Twenty years ago, I wrote a Chem. Commun. feature article entitled “Crystal Engineering:
where from? Where to?”: an update is in order. In this Highlight I argue that molecular crystal …