Tailoring hyaluronic acid hydrogels for biomedical applications

Z Luo, Y Wang, J Li, J Wang, Y Yu… - Advanced Functional …, 2023 - Wiley Online Library
Hyaluronic acid (HA) is an attractive anionic polysaccharide polymer with inherent
pharmacological properties and versatile chemical groups for modification. Due to their …

Advances in antimicrobial microneedle patches for combating infections

R Jamaledin, CKY Yiu, EN Zare, LN Niu… - Advanced …, 2020 - Wiley Online Library
Skin infections caused by bacteria, viruses and fungi are difficult to treat by conventional
topical administration because of poor drug penetration across the stratum corneum. This …

Zn‐MOF encapsulated antibacterial and degradable microneedles array for promoting wound healing

S Yao, J Chi, Y Wang, Y Zhao, Y Luo… - Advanced Healthcare …, 2021 - Wiley Online Library
An infected skin wound caused by external injury remains a serious challenge in clinical
practice. Wound dressings with the properties of antibacterial activity and potent …

X-ray-activated polymerization expanding the frontiers of deep-tissue hydrogel formation

H Zhang, B Tang, B Zhang, K Huang, S Li… - Nature …, 2024 - nature.com
Photo-crosslinking polymerization stands as a fundamental pillar in the domains of
chemistry, biology, and medicine. Yet, prevailing strategies heavily rely on ultraviolet/visible …

Glucose-responsive microneedle patch for closed-loop dual-hormone delivery in mice and pigs

C Yang, T Sheng, W Hou, J Zhang, L Cheng… - Science …, 2022 - science.org
Insulin and glucagon secreted from the pancreas with dynamic balance play a vital role in
regulating blood glucose levels. Although distinct glucose-responsive insulin delivery …

[HTML][HTML] Stimuli-responsive transdermal microneedle patches

P Makvandi, R Jamaledin, G Chen… - Materials Today, 2021 - Elsevier
Microneedle (MN) patches consisting of miniature needles have emerged as a promising
tool to perforate the stratum corneum and translocate biomolecules into the dermis in a …

Microneedle sensors for point‐of‐care diagnostics

Y Hu, E Chatzilakou, Z Pan, G Traverso… - Advanced …, 2024 - Wiley Online Library
Abstract Point‐of‐care (POC) has the capacity to support low‐cost, accurate and real‐time
actionable diagnostic data. Microneedle sensors have received considerable attention as an …

Design principles of microneedles for drug delivery and sampling applications

Z Le, J Yu, YJ Quek, B Bai, X Li, Y Shou, B Myint, C Xu… - Materials Today, 2023 - Elsevier
Microneedles technology is a powerful platform to achieve efficient transdermal delivery of
bioactive molecules for local or systemic therapies attributing to their minimally invasive …

Microneedle-mediated transdermal delivery of biopharmaceuticals

HX Nguyen, CN Nguyen - Pharmaceutics, 2023 - mdpi.com
Transdermal delivery provides numerous benefits over conventional routes of
administration. However, this strategy is generally limited to a few molecules with specific …

Hyaluronic acid based microneedle array: Recent applications in drug delivery and cosmetology

I Saha, VK Rai - Carbohydrate Polymers, 2021 - Elsevier
Microneedles are micron-sized arrays of needles that facilitate drug delivery for local and
systemic effects. Hyaluronic acid (HA) is a glycosaminoglycan and is an indigenous …