Cheating evolution: engineering gene drives to manipulate the fate of wild populations

J Champer, A Buchman, OS Akbari - Nature Reviews Genetics, 2016 - nature.com
Engineered gene drives—the process of stimulating the biased inheritance of specific genes—
have the potential to enable the spread of desirable genes throughout wild populations or to …

Behavioural effects of temperature on ectothermic animals: unifying thermal physiology and behavioural plasticity

PK Abram, G Boivin, J Moiroux, J Brodeur - Biological Reviews, 2017 - Wiley Online Library
Temperature imposes significant constraints on ectothermic animals, and these organisms
have evolved numerous adaptations to respond to these constraints. While the impacts of …

[HTML][HTML] Non-canonical odor coding in the mosquito

M Herre, OV Goldman, TC Lu, G Caballero-Vidal, Y Qi… - Cell, 2022 - cell.com
Aedes aegypti mosquitoes are a persistent human foe, transmitting arboviruses including
dengue when they feed on human blood. Mosquitoes are intensely attracted to body odor …

Mosquito brains encode unique features of human odour to drive host seeking

Z Zhao, JL Zung, A Hinze, AL Kriete, A Iqbal… - Nature, 2022 - nature.com
A globally invasive form of the mosquito Aedes aegypti specializes in biting humans, making
it an efficient disease vector. Host-seeking female mosquitoes strongly prefer human odour …

Development of a confinable gene drive system in the human disease vector Aedes aegypti

M Li, T Yang, NP Kandul, M Bui, S Gamez, R Raban… - Elife, 2020 - elifesciences.org
Aedes aegypti is the principal mosquito vector for many arboviruses that increasingly infect
millions of people every year. With an escalating burden of infections and the relative failure …

Genome editing: A perspective on the application of CRISPR/Cas9 to study human diseases

DR Rodríguez-Rodríguez… - International …, 2019 - spandidos-publications.com
Genome editing reemerged in 2012 with the development of CRISPR/Cas9 technology,
which is a genetic manipulation tool derived from the defense system of certain bacteria …

[HTML][HTML] An engineered orco mutation produces aberrant social behavior and defective neural development in ants

H Yan, C Opachaloemphan, G Mancini, H Yang… - Cell, 2017 - cell.com
Ants exhibit cooperative behaviors and advanced forms of sociality that depend on
pheromone-mediated communication. Odorant receptor neurons (ORNs) express specific …

[HTML][HTML] Aedes aegypti mosquitoes detect acidic volatiles found in human odor using the IR8a pathway

JI Raji, N Melo, JS Castillo, S Gonzalez, V Saldana… - Current Biology, 2019 - cell.com
Mosquitoes use olfaction as a primary means of detecting their hosts. Previously, the
functional ablation of a family of Aedes aegypti olfactory receptors, the odorant receptors …

Evolution of a central neural circuit underlies Drosophila mate preferences

LF Seeholzer, M Seppo, DL Stern, V Ruta - Nature, 2018 - nature.com
Courtship rituals serve to reinforce reproductive barriers between closely related species.
Drosophila melanogaster and Drosophila simulans exhibit reproductive isolation, owing in …

Orco mutagenesis causes loss of antennal lobe glomeruli and impaired social behavior in ants

W Trible, L Olivos-Cisneros, SK McKenzie, J Saragosti… - Cell, 2017 - cell.com
Life inside ant colonies is orchestrated with diverse pheromones, but it is not clear how ants
perceive these social signals. It has been proposed that pheromone perception in ants …