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Childhood obesity from the genes to the epigenome
S Sivakumar, D Lama, N Rabhi - Frontiers in Endocrinology, 2024 - frontiersin.org
The prevalence of obesity and its associated comorbidities has surged dramatically in recent
decades. Especially concerning is the increased rate of childhood obesity, resulting in …
decades. Especially concerning is the increased rate of childhood obesity, resulting in …
[HTML][HTML] Model construction and clinical therapeutic potential of engineered cardiac organoids for cardiovascular diseases
Y Wang, Y Hou, T Hao… - Biomaterials …, 2024 - pmc.ncbi.nlm.nih.gov
Cardiovascular diseases cause significant morbidity and mortality worldwide. Engineered
cardiac organoids are being developed and used to replicate cardiac tissues supporting …
cardiac organoids are being developed and used to replicate cardiac tissues supporting …
Small left ventricle in patients with atrial fibrillation is associated with increased cardiovascular risk
M Li, L Ren, L He, Y Lai, J Wang, S Li, X Peng… - Journal of the American …, 2024 - jacc.org
Background It is still unclear whether small left ventricle (LV) is an adverse structural
prognostic feature in patients with atrial fibrillation (AF). Objectives The purpose of this study …
prognostic feature in patients with atrial fibrillation (AF). Objectives The purpose of this study …
Roles of gut microbiota in androgenetic alopecia: insights from Mendelian randomization analysis
H Fu, T Xu, W Zhao, L Jiang, S Shan - Frontiers in Microbiology, 2024 - frontiersin.org
Background Androgenetic alopecia (AGA) is the most common type of androgen-associated
hair loss. Previous studies have indicated an association between the gut microbiota and …
hair loss. Previous studies have indicated an association between the gut microbiota and …
Prenatal exposure to metal mixtures, body mass index trajectories in early life and effect modifiers: Insights from a prospective birth cohort study
C Yang, X Sun, H Liu, L Yu, S Xu, A Zhou… - Journal of Hazardous …, 2024 - Elsevier
Current scientific knowledge is insufficient on the effects of metal mixtures on early life
growth trajectories. This study included 7118 mother-infant pairs from a Chinese birth cohort …
growth trajectories. This study included 7118 mother-infant pairs from a Chinese birth cohort …
Is lower birthweight truly causal for increased cardiovascular risk?
Ardissino et al. 1 present a Mendelian randomization (MR) study suggesting that lower
birthweight is causal for increased risk of coronary artery disease. We argue that this …
birthweight is causal for increased risk of coronary artery disease. We argue that this …
Integrative proteomic analyses across common cardiac diseases yield mechanistic insights and enhanced prediction
Cardiac diseases represent common highly morbid conditions for which molecular
mechanisms remain incompletely understood. Here we report the analysis of 1,459 protein …
mechanisms remain incompletely understood. Here we report the analysis of 1,459 protein …
Genetic analyses of birthweight and cardiovascular disease
This commentary refers to 'Birth weight influences cardiac structure, function, and disease
risk: evidence of a causal association', by M. Ardissino et al., https://doi …
risk: evidence of a causal association', by M. Ardissino et al., https://doi …
Small left ventricular chamber size and mortality in a large general population
Enlargement of the left ventricle (LV) is an important marker of adverse cardiac remodeling
and poor prognosis. Previous studies demonstrated increased cardiovascular risk in small …
and poor prognosis. Previous studies demonstrated increased cardiovascular risk in small …
Multi‐Organ Phenotypes of Offspring Born Following Hypertensive Disorders of Pregnancy: A Systematic Review
Background Hypertensive pregnancies are associated with an increased risk of
cardiovascular and neurological diseases in the offspring during later life. However, less is …
cardiovascular and neurological diseases in the offspring during later life. However, less is …