Recent advancement of piperidine moiety in treatment of cancer-A review
Piperidine is an important pharmacophore, a privileged scaffold and an excellent
heterocyclic system in the field of drug discovery which provides numerous opportunities in …
heterocyclic system in the field of drug discovery which provides numerous opportunities in …
1, 8‐Naphthyridine derivatives: A review of multiple biological activities
A Madaan, R Verma, V Kumar, AT Singh… - Archiv der …, 2015 - Wiley Online Library
The 1, 8‐naphthyridine group of compounds have gained special attention of researchers
on account of their demonstrating a variety of interesting biological activities. A wide range of …
on account of their demonstrating a variety of interesting biological activities. A wide range of …
Ultrasound-based synthesis, SC-XRD, NMR, DFT, HSA of new Schiff bases derived from 2-aminopyridine: Experimental and theoretical studies
The present work is related to the rapid and efficient preparation of Schiff bases (1 and 2) by
reaction of 2-aminopyridine derivatives with 3-ethoxysalicylaldehyde under ultrasonic …
reaction of 2-aminopyridine derivatives with 3-ethoxysalicylaldehyde under ultrasonic …
Synthesis, characterization, molecular docking and cytotoxicity studies on N-benzyl-2-isonicotinoylhydrazine-1-carbothioamide and its metal complexes
Abstract N-benzyl-2-isonicotinoylhydrazine-1-carbothioamide (H 3 L) and its complexes with
Co (II), Ni (II), Cu (II) and Zn (II) have been synthesized. The metal complexes have been …
Co (II), Ni (II), Cu (II) and Zn (II) have been synthesized. The metal complexes have been …
Anticancer activity of Mannich bases: a review of recent literature
G Roman - ChemMedChem, 2022 - Wiley Online Library
This report summarizes the latest published data on the antiproliferative action and cytotoxic
activity of Mannich bases, a structurally heterogeneous category of chemical entities that …
activity of Mannich bases, a structurally heterogeneous category of chemical entities that …
Structure characterization, DNA binding, molecular docking and antitumor activity of manganese isothiocyanate complex with neocuproine ligand
The novel complex of [Mn (SCN) 2 (neo) 2],(1) was isolated at room temperature by mixing
aqueous solutions of potassium thiocyanate and 2, 9-dimethyl-1, 10-phenanthroline …
aqueous solutions of potassium thiocyanate and 2, 9-dimethyl-1, 10-phenanthroline …
Synthesis, Spectral, Modeling, Docking and Cytotoxicity Studies on 2‐(2‐aminobenzoyl)‐N‐ethylhydrazine‐1‐carbothioamide and its divalent metal complexes
NM Hosny, MA Hussien, R Motawa… - Applied …, 2020 - Wiley Online Library
2‐(2‐aminobenzoyl)‐N‐ethylhydrazine‐1‐carbothioamide (H3L) and its Cu (II), Co (II), Ni (II)
and Zn (II) complexes have been synthesized. The structures of the isolated compounds …
and Zn (II) complexes have been synthesized. The structures of the isolated compounds …
Biological Validation of Novel Polysubstituted Pyrazole Candidates with in Vitro Anticancer Activities
HH Fahmy, NM Khalifa, MMF Ismail, HM El-Sahrawy… - Molecules, 2016 - mdpi.com
With the aim of develo** novel antitumor scaffolds, a novel series of polysubstituted
pyrazole derivatives linked to different nitrogenous heterocyclic ring systems at the C-4 …
pyrazole derivatives linked to different nitrogenous heterocyclic ring systems at the C-4 …
Transition metal complexes of N'-(2-cyanoacetyl) nicotinohydrazide: Synthesis, structural and anticancer activity studies
On reacting the nicotinic hydrazide with 1-cyanoacetyl-3, 5-dimethylpyrazole, a new ligand,
N'-(2-cyanoacetyl) nicotinohydrazide (H 2 L), was produced and characterized using diverse …
N'-(2-cyanoacetyl) nicotinohydrazide (H 2 L), was produced and characterized using diverse …
Exploring novel NH-form resorcinol-based schiff base and its metal complexes: Synthesis, characterization, cytotoxic activity, molecular docking and ADME studies
The research investigates the cytotoxic effects of the stable NH-form of a resorcinol-based
Schiff base (HL) and its metal complexes (Zn (II), Cd (II), Cu (II), Ni (II)) on MCF-7 breast …
Schiff base (HL) and its metal complexes (Zn (II), Cd (II), Cu (II), Ni (II)) on MCF-7 breast …