To predict, prevent, and manage post-traumatic stress disorder (PTSD): a review of pathophysiology, treatment, and biomarkers

GI Al Jowf, ZT Ahmed, RA Reijnders, L de Nijs… - International journal of …, 2023 - mdpi.com
Post-traumatic stress disorder (PTSD) can become a chronic and severely disabling
condition resulting in a reduced quality of life and increased economic burden. The disorder …

Biomarkers in stress related diseases/disorders: diagnostic, prognostic, and therapeutic values

K Dhama, SK Latheef, M Dadar, HA Samad… - Frontiers in molecular …, 2019 - frontiersin.org
Various internal and external factors negatively affect the homeostatic equilibrium of
organisms at the molecular to the whole-body level, inducing the so-called state of stress …

Rodent models of post-traumatic stress disorder: behavioral assessment

A Verbitsky, D Dopfel, N Zhang - Translational psychiatry, 2020 - nature.com
Although the etiology and expression of psychiatric disorders are complex, mammals show
biologically preserved behavioral and neurobiological responses to valent stimuli which …

Single-prolonged stress: a review of two decades of progress in a rodent model of post-traumatic stress disorder

MJ Lisieski, AL Eagle, AC Conti, I Liberzon… - Frontiers in …, 2018 - frontiersin.org
Post-traumatic stress disorder (PTSD) is a common, costly, and often debilitating psychiatric
condition. However, the biological mechanisms underlying this disease are still largely …

Diagnostic biomarkers for posttraumatic stress disorder: promising horizons from translational neuroscience research

V Michopoulos, SD Norrholm, T Jovanovic - Biological psychiatry, 2015 - Elsevier
Posttraumatic stress disorder (PTSD) is a heterogeneous disorder that affects individuals
exposed to trauma (eg, combat, interpersonal violence, and natural disasters). Although its …

[HTML][HTML] A public health perspective of post-traumatic stress disorder

GI Al Jowf, ZT Ahmed, N An, RA Reijnders… - International journal of …, 2022 - mdpi.com
Trauma exposure is one of the most important and prevalent risk factors for mental and
physical ill-health. Prolonged or excessive stress exposure increases the risk of a wide …

Cortisol, heart rate, and blood pressure as early markers of PTSD risk: A systematic review and meta-analysis

MC Morris, N Hellman, JL Abelson, U Rao - Clinical psychology review, 2016 - Elsevier
Individuals with posttraumatic stress disorder (PTSD) typically exhibit altered hypothalamic–
pituitary-adrenal (HPA) function and sympathetic nervous system (SNS) activity. The goals of …

Pre-deployment risk factors for PTSD in active-duty personnel deployed to Afghanistan: a machine-learning approach for analyzing multivariate predictors

K Schultebraucks, M Qian, D Abu-Amara, K Dean… - Molecular …, 2021 - nature.com
Active-duty Army personnel can be exposed to traumatic warzone events and are at
increased risk for develo** post-traumatic stress disorder (PTSD) compared with the …

Posttraumatic growth in populations with posttraumatic stress disorder—A systematic review on growth‐related psychological constructs and biological variables

CF Schubert, U Schmidt… - Clinical psychology & …, 2016 - Wiley Online Library
Posttraumatic growth (PTG) and Posttraumatic Stress Disorder (PTSD) are possible
consequences of trauma. PTG is supposed to emerge from cognitive processes and can …

Conceptualizing traumatic stress and the structure of posttraumatic psychopathology through the lenses of RDoC and HiTOP

SE Hawn, EJ Wolf, Z Neale, MW Miller - Clinical Psychology Review, 2022 - Elsevier
Trauma-related psychopathology, most notably posttraumatic stress disorder (PTSD), poses
unique challenges for psychiatric nosology due to the wide range of symptoms and …