Host-parasite interactions during Plasmodium infection: Implications for immunotherapies

P Chandley, R Ranjan, S Kumar, S Rohatgi - Frontiers in Immunology, 2023 - frontiersin.org
Malaria is a global infectious disease that remains a leading cause of morbidity and mortality
in the develo** world. Multiple environmental and host and parasite factors govern the …

In silico design and immunoinformatics analysis of a universal multi-epitope vaccine against monkeypox virus

S Sanami, S Nazarian, S Ahmad, E Raeisi… - Plos one, 2023 - journals.plos.org
Monkeypox virus (MPXV) outbreaks have been reported in various countries worldwide;
however, there is no specific vaccine against MPXV. In this study, therefore, we employed …

Recent advances on vaccines against malaria: A review

S Malik, Y Waheed - Asian Pacific Journal of Tropical Medicine, 2024 - journals.lww.com
This review aims to summarize the currently viable vaccine strategies including the
approved vaccines and the those in trials for next-generation malaria vaccines. Data on …

Protective Efficacy of Multiple Epitope-Based Vaccine against Hyalomma anatolicum, Vector of Theileria annulata and Crimean–Congo Hemorrhagic Fever Virus

A Nandi, Manisha, V Solanki, V Tiwari, B Sajjanar… - Vaccines, 2023 - mdpi.com
Hyalomma anatolicum is the principal vector for Theileria annulata, T. equi, and T.
Lestoquardi in animals and the Crimean–Congo hemorrhagic fever virus in humans. Due to …

Construction, Expression, and Evaluation of the Naturally Acquired Humoral Immune Response against Plasmodium vivax RMC-1, a Multistage Chimeric Protein

AS Matos, IF Soares, BO Baptista… - International Journal of …, 2023 - mdpi.com
The PvCelTOS, PvCyRPA, and Pvs25 proteins play important roles during the three stages
of the P. vivax lifecycle. In this study, we designed and expressed a P. vivax recombinant …

Enhancing explainable SARS-CoV-2 vaccine development leveraging bee colony optimised Bi-LSTM, Bi-GRU models and bioinformatic analysis

DU Ozsahin, ZS Ameen, AS Hassan, AS Mubarak - Scientific Reports, 2024 - nature.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a single-stranded
RNA virus that caused the outbreak of the coronavirus disease 2019 (COVID-19). The …

Enhancing tuberculosis vaccine development: a deconvolution neural network approach for multi-epitope prediction

AS Mubarak, ZS Ameen, AS Hassan, DU Ozsahin - Scientific Reports, 2024 - nature.com
Tuberculosis (TB) a disease caused by Mycobacterium tuberculosis (Mtb) poses a
significant threat to human life, and current BCG vaccinations only provide sporadic …

Analysis of sequence diversity in Plasmodium falciparum glutamic acid-rich protein (PfGARP), an asexual blood stage vaccine candidate

R Rojrung, N Kuamsab, C Putaporntip… - Scientific Reports, 2023 - nature.com
Glutamic acid-rich protein of Plasmodium falciparum (PfGARP) binds to erythrocyte band 3
and may enhance cytoadherence of infected erythrocytes. Naturally acquired anti-PfGARP …

Computational design of multi-epitope vaccine against Hepatitis C Virus infection using immunoinformatics techniques

S Zubair, F Parvaiz, T Abualait, K Al-Regaiey, T Anwar… - PloS one, 2025 - journals.plos.org
Hepatitis C Virus (HCV) is a blood borne pathogen that affects around 200 million
individuals worldwide. Immunizations against the Hepatitis C Virus are intended to enhance …

Molecular and Immunological Properties of a Chimeric Glycosyl Hydrolase 18 Based on Immunoinformatics Approaches: A Design of a New Anti-Leishmania Vaccine

JE da Cruz Freire, AN Cardeal dos Santos… - ACS Pharmacology & …, 2024 - ACS Publications
Leishmaniasis is a chronic inflammatory zoonotic illness caused by protozoan flagellates
belonging to the Leishmania genus. Current data suggest that over 1 billion people …