Toxicokinetics and metabolism of deoxynivalenol in animals and humans

Y Sun, J Jiang, P Mu, R Lin, J Wen, Y Deng - Archives of toxicology, 2022 - Springer
Deoxynivalenol (DON) is the most widespread mycotoxin in food and feedstuffs, posing a
persistent health threat to humans and farm animals. The susceptibilities of DON vary …

The neurotoxicity of trichothecenes T-2 toxin and deoxynivalenol (DON): Current status and future perspectives

J Zhang, L You, W Wu, X Wang, Z Chrienova… - Food and Chemical …, 2020 - Elsevier
During the last decade, the neurotoxicity of the trichothecenes T-2 toxin and deoxynivalenol
(DON) has been a major concern, and many important findings have been reported on this …

[HTML][HTML] Deoxynivalenol triggers porcine intestinal tight junction disorder: Insights from mitochondrial dynamics and mitophagy

C Zhang, KF Zhang, FJ Chen, YH Chen, X Yang… - Ecotoxicology and …, 2022 - Elsevier
Deoxynivalenol (DON) is universally detected trichothecene in most cereal commodities,
which is considered as a major hazardous material for human and animal health. Intestine is …

Dual near-infrared fluorescence-based lateral flow immunosensor for the detection of zearalenone and deoxynivalenol in maize

Y **, Q Chen, S Luo, L He, R Fan, S Zhang, C Yang… - Food Chemistry, 2021 - Elsevier
A novel dual near-infrared fluorescence-based lateral flow immunosensor was developed to
determine zearalenone and deoxynivalenol in maize. Two near-infrared dyes with distinct …

Detoxification of mycotoxins in agricultural products by non-thermal physical technologies: A review of the past five years

Y Wang, J Shang, M Cai, Y Liu… - Critical Reviews in Food …, 2023 - Taylor & Francis
Mycotoxins produced by Aspergillus spp., Penicillium spp. and Fusarium spp. with small
molecular weight and thermal stability, are highly toxic and carcinogenic secondary …

Deoxynivalenol at no-observed adverse-effect levels aggravates DSS-induced colitis through the JAK2/STAT3 signaling pathway in mice

F Gan, Z Lin, J Tang, X Chen… - Journal of Agricultural and …, 2023 - ACS Publications
The etiology of inflammatory bowel diseases (IBDs) involves complex genetic and
environmental factors such as mycotoxin contamination. Deoxynivalenol (DON), a well …

Recent advances in assessing the effects of mycotoxins using animal models

AF Furian, MR Fighera, LFF Royes… - Current Opinion in Food …, 2022 - Elsevier
Food products are susceptible to mycotoxin contamination. The intoxication produces
distinct signs, depending on mycotoxin, duration, dose, and species susceptibility …

Insights into the intestinal toxicity of foodborne mycotoxins through gut microbiota: A comprehensive review

H Ruan, Y Huang, B Yue, Y Zhang, J Lv… - … Reviews in Food …, 2023 - Wiley Online Library
Mycotoxins, which are fungal metabolites, pose a significant global food safety concern by
extensively contaminating food and feed, thereby seriously threatening public health and …

A proposed role for pro-inflammatory cytokines in damaging behavior in pigs

J Nordgreen, SA Edwards, LA Boyle… - Frontiers in Veterinary …, 2020 - frontiersin.org
Sickness can change our mood for the worse, leaving us sad, lethargic, grumpy and less
socially inclined. This mood change is part of a set of behavioral symptoms called sickness …

Metabolomics in chemical risk analysis–A review

M Hernández-Mesa, B Le Bizec, G Dervilly - Analytica Chimica Acta, 2021 - Elsevier
Exposure to chemical hazards is a growing concern in today's society, and it is of utmost
interest to know the levels of exposure to chemicals and the risks associated with such …