Aberrant B cell signaling plays a critical in role in various systemic and organ-specific
autoimmune diseases. This is supported by genetic evidence by many functional studies in …

Antibodies are critical for providing protection against influenza virus infections. However,
protective humoral immunity against influenza viruses is limited by the antigenic drift and …

Broadly neutralizing antibodies that target epitopes of haemagglutinin on the influenza virus
have the potential to provide near universal protection against influenza virus infection …

Pan-betacoronavirus neutralizing antibodies may hold the key to develo** broadly
protective vaccines against novel pandemic coronaviruses and to more effectively respond …

Dimeric IgA secreted across mucous membranes in response to nonpathogenic taxa of the
microbiota accounts for most antibody production in mammals. Diverse binding specificities …

Monoclonal antibodies (mAbs) are a focus in vaccine and therapeutic design to counteract
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its variants. Here, we …

Avian influenza A virus H7N9 causes severe human infections with> 30% fatality. Currently,
there is no H7N9-specific prevention or treatment for humans. Here, from a 2013 H7N9 …

Human broadly neutralizing antibodies (bnAbs) targeting the hemagglutinin stalk of group 1
influenza A viruses (IAVs) are biased for IGHV1-69 alleles that use phenylalanine (F54) but …

Broadly neutralizing antibodies are critical for protection against both drifted and shifted
influenza viruses. Here, we reveal that first exposure to the 2009 pandemic H1N1 influenza …

Delineating the origins and properties of antibodies elicited by SARS-CoV-2 infection and
vaccination is critical for understanding their benefits and potential shortcomings. Therefore …