The NADPH Link between the Renin Angiotensin System and the Antioxidant Mechanisms in Dopaminergic Neurons

R Franco, J Serrano-Marín, G Navarro… - Antioxidants, 2023 - mdpi.com
The renin angiotensin system (RAS) has several components including signaling peptides,
enzymes, and membrane receptors. The effort in characterizing this system in the periphery …

Oncogene-mediated metabolic gene signature predicts breast cancer outcome

M Aslan, EC Hsu, FJ Garcia-Marques, A Bermudez… - NPJ Breast …, 2021 - nature.com
Breast cancer remains the second most lethal cancer among women in the United States
and triple-negative breast cancer is the most aggressive subtype with limited treatment …

[HTML][HTML] Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer

CR Silvers, H Miyamoto, EM Messing, GJ Netto… - Oncotarget, 2017 - ncbi.nlm.nih.gov
The mechanisms of bladder cancer progression are unknown, and new treatments and
biomarkers are needed. Patient urinary extracellular vesicles (EVs) derive in part from …

Jejunal mucosa proteomics unravel metabolic adaptive processes to mild chronic heat stress in dairy cows

F Koch, D Albrecht, S Görs, B Kuhla - Scientific Reports, 2021 - nature.com
Climate change affects the duration and intensity of heat waves during summer months and
jeopardizes animal health and welfare. High ambient temperatures cause heat stress in …

Investigating neuron degeneration in huntington's disease using RNA-Seq based transcriptome study

NP Sneha, SAP Dharshini, Y Taguchi, MM Gromiha - Genes, 2023 - mdpi.com
Huntington's disease (HD) is a progressive neurodegenerative disorder caused due to a
CAG repeat expansion in the huntingtin (HTT) gene. The primary symptoms of HD include …

[HTML][HTML] Genome-wide association study for weight loss at the end of dry-curing of hams produced from purebred heavy pigs

S Faggion, V Bonfatti, P Carnier - Animals, 2024 - mdpi.com
Simple Summary Understanding the genetics of traits related to curing is crucial to both
revealing the biological insights and effectively designing pig selective breeding programs …

Transportin-2 plays a critical role in nucleocytoplasmic shuttling of oestrogen receptor-α

T Moriyama, Y Yoneda, M Oka, M Yamada - Scientific Reports, 2020 - nature.com
Oestrogen receptor-α (ERα) shuttles continuously between the nucleus and the cytoplasm,
and functions as an oestrogen-dependent transcription factor in the nucleus and as an …

Systems-wide analysis unravels the new roles of CCM signal complex (CSC)

J Abou-Fadel, M Vasquez, B Grajeda, C Ellis, J Zhang - Heliyon, 2019 - cell.com
Cerebral cavernous malformations (CCMs) are characterized by abnormally dilated
intracranial capillaries that result in increased susceptibility to stroke. Three genes have …

Anti-Cancer Mechanisms of Diarylpentanoid MS17 (1, 5-Bis (2-hydroxyphenyl)-1, 4-pentadiene-3-one) in Human Colon Cancer Cells: A Proteomics Approach

KW Hon, SA Zainal Abidin, F Abas, I Othman… - International Journal of …, 2024 - mdpi.com
Diarylpentanoids are synthesized to overcome curcumin's poor bioavailability and low
stability to show enhanced anti-cancer effects. Little is known about the anti-cancer effects of …

Adaptogen Technology for Skin Resilience Benefits

A Cavagnino, L Breton, C Ruaux, C Grossgold… - Cosmetics, 2023 - mdpi.com
(1) Background: Skin undergoes constant changes, providing capabilities to repair and
renovate its constituents once damaged and a fundamental shield to contrast environmental …