ToxCodAn-Genome: an automated pipeline for toxin-gene annotation in genome assembly of venomous lineages

PG Nachtigall, AM Durham, DR Rokyta… - …, 2024 - academic.oup.com
Background The rapid development of sequencing technologies resulted in a wide
expansion of genomics studies using venomous lineages. This facilitated research focusing …

A novel metalloproteinase-derived cryptide from Bothrops cotiara venom inhibits angiotensin-converting enzyme activity

JG Miyamoto, ES Kitano, A Zelanis, PG Nachtigall… - Biochimie, 2024 - Elsevier
Snake venoms are primarily composed of proteins and peptides, which selectively interact
with specific molecular targets, disrupting prey homeostasis. Identifying toxins and the …

Venom composition of neglected bothropoid snakes from the Amazon rainforest: ecological and toxinological implications

LA Freitas-de-Sousa, M Colombini, VC Souza… - Toxins, 2024 - mdpi.com
Snake venoms have evolved in several families of Caenophidae, and their toxins have been
assumed to be biochemical weapons with a role as a trophic adaptation. However, it …

Unveiling Novel Kunitz- and Waprin-Type Toxins in the Micrurus mipartitus Coral Snake Venom Gland: An In Silico Transcriptome Analysis

M Saldarriaga-Córdoba, C Clavero-León… - Toxins, 2024 - mdpi.com
Kunitz-type peptide expression has been described in the venom of snakes of the Viperidae,
Elapidae and Colubridae families. This work aimed to identify these peptides in the venom …

Comparing morphological and secretory aspects of cephalic glands among the New World coral snakes brings novel insights on their biological roles

L de Oliveira, PG Nachtigall, VL Vialla, PF Campos… - Toxicon, 2023 - Elsevier
Oral and other cephalic glands have been surveyed by several studies with distinct
purposes. Despite the wide diversity and medical relevance of the New World coral snakes …

Highly conserved and extremely variable: The paradoxical pattern of toxin expression revealed by comparative venom-gland transcriptomics of Phalotris (Serpentes …

OM Entiauspe-Neto, PG Nachtigall, M Borges-Martins… - Toxicon, 2024 - Elsevier
Although non-front fanged snakes account for almost two-thirds of snake diversity, most
studies on venom composition and evolution focus exclusively on front-fanged species …

Toxic Forms Most Beautiful: The Evolutionary Dynamics of Rear-Fanged Snake Venoms

P Cerda - 2023 - deepblue.lib.umich.edu
A chief goal in evolutionary biology is to understand how ecological factors and genetic
processes influence the evolution of traits. However, a complicating factor is that traits are …

Rhomb-I, a P–I metalloproteinase from Lachesis muta rhombeata venom degrades vessel extra cellular matrix components and impairs platelet aggregation

VG de Alvarenga, LS Oliveira, GO Santos… - Toxicon, 2023 - Elsevier
Abstract Rhomb-I, a 23-kDa metalloproteinase was isolated from L. m. rhombeata venom. Its
dimethylcasein proteolysis was abolished by metal chelators, and slightly enhanced by Ca …

Unveiling Novel Kunitz-and Waprin-Type Toxins in the Micrurus mipartitus Coral Snake Venom Gland: An In Silico Transcriptome Analysis

JP Rey Suárez, V Nuñez Rangel, JF Alzate Restrepo… - 2024 - bibliotecadigital.udea.edu.co
Kunitz-type peptide expression has been described in the venom of snakes of the Viperidae,
Elapidae and Colubridae families. This work aimed to identify these peptides in the venom …

Análisis transcriptómicos para la caracterización de diversidad de toxinas de veneno en Víboras cabeza de sapo (Bothrocophias: Viperidae: Serpentes).

MA Mejía Guerrero - 2022 - repositorio.uti.edu.ec
Bothrocophias (víboras cabeza de sapo) es un género sudamericano de serpientes que
pertenece a la familia Viperidae. Mientras que la composición y la función del veneno han …