Genetics, epigenetics and transgenerational transmission of obesity in children

N Panera, C Mandato, A Crudele… - Frontiers in …, 2022 - frontiersin.org
Sedentary lifestyle and consumption of high-calorie foods have caused a relentless increase
of overweight and obesity prevalence at all ages. Its presently epidemic proportion is …

Relation between obesity and type 2 diabetes: evolutionary insights, perspectives and controversies

MK Gupta, G Gouda, R Vadde - Current Obesity Reports, 2024 - Springer
Abstract Purpose of Review Since the mid-twentieth century, obesity and its related
comorbidities, notably insulin resistance (IR) and type 2 diabetes (T2D), have surged …

Polymorphisms of fat mass and obesity-associated gene in the pathogenesis of child and adolescent metabolic syndrome

Y Song, H Wade, B Zhang, W Xu, R Wu, S Li, Q Su - Nutrients, 2023 - mdpi.com
Childhood metabolic syndrome (MetS) is prevalent around the world and is associated with
a high likelihood of suffering from severe diseases such as cardiovascular disease later in …

Evidence from a meta-analysis for association of MC4R rs17782313 and FTO rs9939609 polymorphisms with susceptibility to obesity in children

SA Dastgheib, R Bahrami, S Setayesh, S Salari… - Diabetes & Metabolic …, 2021 - Elsevier
Background and aim The aim of this study was to evaluate the association of MC4R
rs17782313 and FTO rs9939609 polymorphisms with childhood obesity. Methods A …

Association of FTO variants rs9939609 and rs1421085 with elevated sugar and fat consumption in adult obesity

S Poosri, U Boonyuen, C Chupeerach… - Scientific Reports, 2024 - nature.com
This cross-sectional study explores the impact of FTO gene single nucleotide
polymorphisms (SNPs) rs9939609 and rs1421085 on dietary habits contributing to obesity …

The rs17782313 polymorphism near MC4R gene confers a high risk of obesity and hyperglycemia, while PGC1α rs8192678 polymorphism is weakly correlated with …

Y Zhang, S Li, H Nie, X Wang, X Li, J Wen… - Frontiers in …, 2023 - frontiersin.org
Background The relationships of the rs17782313 polymorphism near melanocortin 4
receptor gene (MC4R) and the rs8192678 polymorphism in peroxisome proliferator …

Identification and association of single nucleotide polymorphisms of the FTO gene with indicators of overweight and obesity in a young Mexican population

A Chama-Avilés, KL Flores-Viveros, JA Cabrera-Ayala… - Genes, 2023 - mdpi.com
(1) Background: obesity is a global public health problem; various factors have been
associated with this disease, and genetic factors play a very important role. Previous studies …

[HTML][HTML] Anthropometric and body composition analysis in obese and non-obese subjects in three major cities in Indonesia: A cross-sectional study

NK Fitri, DK Sari, NI Lipoeto - Human Nutrition & Metabolism, 2024 - Elsevier
Background Screening is needed for the early detection of obesity, but if detection through
anthropometric examinations and body composition measurements is not correct, then …

Genetic and epigenetic origins of childhood obesity

M Bustos-Aibar, Á Torres-Martos, Á Gil, CM Aguilera - Childhood Obesity, 2025 - Elsevier
The escalating occurrence of childhood and adolescent obesity on a global scale is a
significant issue of apprehension. Individuals develo** obesity during childhood are …

Genetic association of FTO gene polymorphisms with obesity and its related phenotypes: A case-control study

T Sharma, B Badaruddoza - Journal of Cardiovascular and …, 2024 - pmc.ncbi.nlm.nih.gov
Introduction: FTO gene belongs to the non-heme Fe (II) and 2 oxoglutarate-dependent
dioxygenase superfamily. Polymorphisms within the first intron of the FTO gene have been …